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全部话题 - 话题: genetic
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X*******8
发帖数: 3895
1
刚才看有人在“请教一个转基因问题”,故把下面一篇文章转过来,没有翻译,有兴趣
的自己看吧。
http://www.holistichealthsecrets.com/alternativehealth/genetica
modified-foods-healthy-to-eat/
Are Genetically Modified Foods Healthy to Eat?
July 14th, 2009adminLeave a commentGo to comments
The topic of Genetically Modified Food (GMOs) can be confusing. On one side
we have big Pharma
companies touting studies that show that Genetically Modified Food is
perfectly safe for consumption. On
the other hand, we have wholistic health groups and speakers s... 阅读全帖
c********r
发帖数: 1125
2
来自主题: Biology版 - Journal "Genetics"
我还是回中文比较舒服。。
我个人的一点浅见:
-GENETICS是遗传领域很好的专业杂志,历史悠久。而且对于传统遗传领域和模式生物
是不错的杂志(population遗传我不懂,没发言权)。
-审稿人很多是领域里多年的老资格同志,问的问题有时候也很CRITICAL。总体倾向是
相信体内DATA,而且文章的工作量往往不小。
-很多大牛的实验室也会发GENETICS的文章,我个人理解主要有两种:
1.做了一个筛选,把筛选的工作发表了(通常只是讲怎么筛的,有意思的基因的跟进工
作不在里面包含)。
2.某个基因的功能研究,可以做的很彻底,但是一般MOLECULAR机制比较欠缺,而且不
是什么热门基因。所以很多GENETICS上的文章可以完全没有体外实验,但是遗传部分要
STRONG。
3.低等-冷门模式生物的天堂:线虫,果蝇,酵母,真菌甚至玉米等等都是GENETICS上
常客。老鼠如果没有机制研究一般会发在DEV BIOLOGY或者GENESIS上面。
-至于老板只能发GENETICS。。。如果没有高级的文章。。我只能说他遗传功底不错,
但是手段太单一了。。现在在有模式生物体内试验的基础上稍微... 阅读全帖
b*********g
发帖数: 1
3
Experimental evolution领域,做了一年多的纤毛虫变异积累实验(1000代),出了一批
数据,分析结果
比较理想(fitness assay 和 simulation结合,比较同一细胞内演化1000代后生殖核
和体细胞核内的
自发变异率及变异对fitness的影响),数据都能解释圆了,导师说投Genetics,说比
plos genetics在
evolutionary genetics方向上口碑要好(以前在其他模式生物上做的变异积累实验很
多发表在
genetics上),虽然影响因子genetics不高。
刚才瞅了下plos genetics的IF(9左右)比genetics(4左右)高好多,看了下中科院SCI
划区,俩杂志
都在二区。
在杂志上多想了是想着以后如果回国,俩杂志是不是有不同效应,毕竟大多数人现在只
看IF。
到底该选哪个杂志,望请高人指教,非常感谢。
s*****0
发帖数: 357
4
其实生物统计范围很广,一般学校里的program都会有这么几大支: clinical trials,
survival, 以及statistical genetics等等. 当然有些bioinformatics也纳入
biostatistics的范畴,但bioinformatics顶多算跟biostat有交叉,不能算传统的
biostatistics. biostat的training跟bioinfo的focus不一样.要细分,这几大支还能分
出很多小支来,比如statistical genetics,可以做gene mapping/genetic association
study, evolutionary genetics, population genetics, genetic epidemiology, 动
植物breeding等. 而在industry,生统最常见的是做clinical trials, 而statistical
genetics 的focus虽然有些工业界的opening (比如agriculture公司的育种或者一些
personal medicine以
t**********8
发帖数: 1683
5
【 以下文字转载自 Military 讨论区 】
发信人: twinlight198 (雙灯), 信区: Military
标 题: Race differences in average IQ are largely genetic
发信站: BBS 未名空间站 (Mon May 20 22:37:57 2013, 美东)
Race differences in average IQ are largely genetic
Published on April 26, 2005 at 5:29 PM · 122 Comments
inShare.2A 60-page review of the scientific evidence, some based on state-
of-the-art magnetic resonance imaging (MRI) of brain size, has concluded
that race differences in average IQ are largely genetic.
The lead article in the J... 阅读全帖
w******6
发帖数: 1093
6
虽然已经做了决定,还是想来版上吐槽一下,就当树洞,记录下整个过程吧。
希望不要引起姐妹们反感,其实我也不是很祥林嫂,大部分时间我还是挺乐观的。
因为我的OB只有周一接诊,上周二做完大B超,只见了genetic counselor。B超结果是
左手左脚显示不清,可能是并指。genetic counselor的意见就是,根据现在的结果不
能做出任何的结论,因为胎儿还太小,要等到孩子更大一些才看得清。做B超的时候,
LD一直守在旁边,他说,是宝宝不配合,所以不给机会让医生看清,“等到19周再做B
超的时候,肯定五个手指全张开了。”
我还是很担心,因为之前严重的水肿和后背的水瘤,我觉得不可能就完全不留痕迹地消
失了。但是看到LD挺乐观的,我也就慢慢开心起来了,也决心不想坏的可能性,只顺其
自然吧。
昨天又是去见OB的时间。
一般例行检查的顺序是,先是医生的助手来,分析两次接诊之间的一些检查的结果,听
胎心,量血压什么的,然后医生才来。
开始我听到了宝宝有力的心跳,好像在努力地展示他在顽强地与命运抗争,努力地想活
下来。我心里说不出的滋味。
然后,她(医生助手)坐下看B超的结果,结果她给了我... 阅读全帖
i*******m
发帖数: 580
7
【 以下文字转载自 Fitness 讨论区 】
发信人: iloveplmm (PLMM也LOVE ME), 信区: Fitness
标 题: no genetic modified bean in US market
发信站: BBS 未名空间站 (Tue Oct 14 14:57:41 2014, 美东)
Do you believe in it
http://delcarmenfoods.com/faqs/non-gmo/
Are the beans you use in your products non-GMO (genetically-modified
organisms)
Per the Bean Improvement Cooperative (BIC), there are currently no
commercially produced or imported GMO-beans in the U.S. This includes all
commercial varieties of dry and snap beans.
Beans are a recal... 阅读全帖
t**********8
发帖数: 1683
8
Race differences in average IQ are largely genetic
Published on April 26, 2005 at 5:29 PM · 122 Comments
inShare.2A 60-page review of the scientific evidence, some based on state-
of-the-art magnetic resonance imaging (MRI) of brain size, has concluded
that race differences in average IQ are largely genetic.
The lead article in the June 2005 issue of Psychology, Public Policy and Law
, a journal of the American Psychological Association, examined 10
categories of research evidence from around th... 阅读全帖
w****s
发帖数: 122
9
【 以下文字转载自 Biology 讨论区 】
发信人: wszcas (roy), 信区: Biology
标 题: 真诚求审稿机会:statistical genetics and genetics epidemiology
发信站: BBS 未名空间站 (Thu Feb 27 17:01:23 2014, 美东)
PhD in statistical genetics and genetics epidemiology, currently a post-doc
at UCSF.
expertise: genome-wide association studies, disease heritability estimation,
population stratification and candidate-gene based/genome-wide association
analysis, admixture mapping,Meta-analysis of GWAS,confounding and
heterogeneity in GWAS
Thanks!!!
i*******m
发帖数: 580
10
来自主题: Fitness版 - no genetic modified bean in US market
Do you believe in it
http://delcarmenfoods.com/faqs/non-gmo/
Are the beans you use in your products non-GMO (genetically-modified
organisms)
Per the Bean Improvement Cooperative (BIC), there are currently no
commercially produced or imported GMO-beans in the U.S. This includes all
commercial varieties of dry and snap beans.
Beans are a recalcitrant species (unlike corn, tomatoes or soybeans); thus,
have not been amenable to genetic engineering or modification from other
genetic sources. No Genet... 阅读全帖
c********r
发帖数: 1125
11

我不是完全同意你得观点(有关genomics)。
plos genetics上面确实有genomics文章,但是大多数文章还是很偏传统genetics/
development的。因子之所以高是因为很多大牛中牛(原来只是小牛灌水乐园)开始大
量投这个杂志了,所以才水涨船高的。
从发育/遗传学科角度来说,有plos genetics是个好事情。原来如果有一个不错的故
事,但是级别又不到dev cell,ncb的话,就很尴尬,development/genetics老牌,但
是因子比较低,current biology不是所有故事都接受(它家喜欢新鲜的东西)。
所以现在对于发育/遗传领域来说,有好的表型,有一定的体外功能/机制研究,但是
发现又没有重要到崭新的突破/或者把整个pathway/机制搞得特别清楚的文章,plos
genetics我觉得就是最好的选择了。
当然学科和学科不同,embo 上面有很多分子/生化的工作很出色,这两个杂志的定位
实际还是挺不一样的。
c*****t
发帖数: 625
12
medical genetics 如果想学医的话,可以考虑两条路:
1. medical genetics counseling, 读个master即可,在美国做counseling很赚钱,职
业轻松。
2.考board,申请这个5年的residency+fellowship.就业面很窄,而且最后当医生要考
两个certificates, 好像是internal medicine还有genetics。我读的genetics 博士
,都没有申请。太累,放弃。
3.如果在国内有医学学位,有过住院医培训,可以申请这边类似于internal medicine
combined genetics fellowship,两年还是四年忘了。出来以后基本上80%时间做科研,
20%看病人。不用考board。我有个巴西学妹读的这个,非常适合愿意做科研的人。
w****s
发帖数: 122
13
【 以下文字转载自 Biology 讨论区 】
发信人: wszcas (roy), 信区: Biology
标 题: 真诚求审稿机会:statistical genetics and genetics epidemiology
发信站: BBS 未名空间站 (Thu Feb 27 17:01:23 2014, 美东)
PhD in statistical genetics and genetics epidemiology, currently a post-doc
at UCSF.
expertise: genome-wide association studies, disease heritability estimation,
population stratification and candidate-gene based/genome-wide association
analysis, admixture mapping,Meta-analysis of GWAS,confounding and
heterogeneity in GWAS
Thanks!!!
F*V
发帖数: 3978
14
Race differences in average IQ are largely genetic
Published on April 26, 2005 at 5:29 PM · 122 Comments
inShare.2A 60-page review of the scientific evidence, some based on state-
of-the-art magnetic resonance imaging (MRI) of brain size, has concluded
that race differences in average IQ are largely genetic.
The lead article in the June 2005 issue of Psychology, Public Policy and Law
, a journal of the American Psychological Association, examined 10
categories of research evidence from around th... 阅读全帖
m*****7
发帖数: 366
15
我是做Pancreatic Cancer genetics方向的,包括像germline genetic variant/
mutation (GWAS和whole exome sequencing),somatic genetic variants都有涉及,
欢迎也是做胰腺癌genetics一块的同行(包括population/clinic level或basic
science level)一起合作讨论。
多谢!
h***a
发帖数: 312
16
http://www.aaemonline.org/gmopressrelease.html
The American Academy Of Environmental Medicine Calls For
Immediate Moratorium On Genetically Modified Foods
Wichita, KS - The American Academy of Environmental Medicine (AAEM) today
released its position paper on Genetically Modified foods stating that "GM
foods pose a serious health risk" and calling for a moratorium on GM foods.
Citing several animal studies, the AAEM concludes "there is more than a
casual association between GM foods and adverse ... 阅读全帖
r**********e
发帖数: 587
17
来自主题: Biology版 - Journal "Genetics"
How's the journal "Genetics" ?
Seems no longer high-impact(maybe high-impact long time ago),but very
professional one.
I see a young assistant professor(doing population genetics), he publishes
lots of "Genetics" paper as sole first-author, then how's this professor?
Is "Genetics" publication a indication of excellence of research level?
This actually throws another question: for some "cold" "very professional"
field(even for virus field), it's hard to have paper on CNS; so if one
continually pu... 阅读全帖
g*********t
发帖数: 271
18
帮忙发招聘贴,实验室平台都已经建好了,老板也是大老板,现在实验室做的方向是测
序,有兴趣的请积极申请。
Postdoctoral training is available in the Division of Human Genetics,
Department of Psychiatry, Yale University School of Medicine, for work on
NIH-funded projects. We study genetics of substance dependence and other
psychiatric disorders, using linkage, association, GWAS, and deep sequencing
. The ideal candidate should hold an MD or PhD, and be well-motivated, with
a strong background in the field of human genetics, including knowledge of
se... 阅读全帖
m*****7
发帖数: 366
19
我是做Pancreatic Cancer genetics方向的,包括像germline genetic variant/
mutation (GWAS和whole exome sequencing),somatic genetic variants都有涉及,
欢迎也是做胰腺癌genetics一块的同行(包括population/clinic level或basic
science level)一起合作讨论。
多谢!
J*******x
发帖数: 45
20
还有几年就奔40了,药厂面临合并。自己想着怎么找退路。我有药理毒理的博士学位,
想去考个 American board of medicine genetics 的 certificate . 现在有三个方向
可选择,Clinical Cytogenetics Genetics, Clinical Molecular Genetics,
clinical Biochemical Genetics.如果考虑以后就业和市场需求,我该选择哪个方向呢
?请大家给我点意见,谢谢了!
J*******x
发帖数: 45
21
还有几年就奔40了,药厂面临合并。自己想着怎么找退路。我有药理毒理的博士学位,
想去考个 American board of medicine genetics 的 certificate . 现在有三个方向
可选择,Clinical Cytogenetics Genetics, Clinical Molecular Genetics,
clinical Biochemical Genetics.如果考虑以后就业和市场需求,我该选择哪个方向呢
?请大家给我点意见,谢谢了!
m*****7
发帖数: 366
22
我是做Pancreatic Cancer genetics方向的,包括像germline genetic variant/
mutation (GWAS和whole exome sequencing),somatic genetic variants都有涉及,
欢迎也是做胰腺癌genetics一块的同行(包括population/clinic level或basic
science level)一起合作讨论。
多谢!
J*******x
发帖数: 45
23
来自主题: Medicalpractice版 - 请大家给点意见 我该选择哪个genetics?
还有几年就奔40了,药厂面临合并。自己想着怎么找退路。我有药理毒理的博士学位,
想去考个 American board of medicine genetics 的 certificate . 现在有三个方向
可选择,Clinical Cytogenetics Genetics, Clinical Molecular Genetics,
clinical Biochemical Genetics.如果考虑以后就业和市场需求,我该选择哪个方向呢
?请大家给我点意见,谢谢了!
J*******x
发帖数: 45
24
还有几年就奔40了,药厂面临合并。自己想着怎么找退路。我有药理毒理的博士学位,
想去考个 American board of medicine genetics 的 certificate . 现在有三个方向
可选择,Clinical Cytogenetics Genetics, Clinical Molecular Genetics,
clinical Biochemical Genetics.如果考虑以后就业和市场需求,我该选择哪个方向呢
?请大家给我点意见,谢谢了!
r*****s
发帖数: 184
25
【 以下文字转载自 Military 讨论区 】
发信人: rooibos (rooibos), 信区: Military
标 题: Monsanto: Report Genetically Modified Corn Causes Organ Damage In RatsHershey
发信站: BBS 未名空间站 (Mon Feb 22 19:14:01 2010, 美东)
http://blogs.barrons.com/stockstowatchtoday/2010/01/13/monsanto-report-genetically-modified-corn-causes-organ-damage-in-rats/
By Eric Savitz
Genetically-modified corn sold by Monsanto (MON) causes organ damage in rats
, according to a paper by three French scientists published in the
International Journal o
l****p
发帖数: 27354
26
你们要是真学术的话,要看看现实世界。
Broken Promises of Genetically Modified Crops
By KARL RUSSELL and DANNY HAKIM OCT. 29, 2016
https://www.nytimes.com/interactive/2016/10/30/business/gmo-crops-pesticides
.html?mcubz=1
About 20 years ago, the United States and Canada began introducing genetic
modifications in agriculture. Europe did not embrace the technology, yet it
achieved increases in yield and decreases in pesticide use on a par with, or
even better than, the United States, where genetically modified crops ... 阅读全帖
b********d
发帖数: 5
27
The Section on Statistical Genetics in the Department of Biostatistics at
the University of Alabama at Birmingham is accepting applications from
statistical and other scientists for postdoctoral positions in Statistical
Genetics, Genetic Epidemiology, and/or Bioinformatics. Starting dates are
open and flexible. Salary is commensurate with qualifications but in all
cases equals or exceeds NIH post-doctoral stipends. No citizenship
requirement. For more information, please refer to http://www.soph
s*******9
发帖数: 177
28
来自主题: NextGeneration版 - 这两个genetic screening plan 哪个好?
我们这个医院的所有的OB 都不管 genetic screening测试, 都归专门的genetic
counselor管。会见了genetic counselor, 说如果先不准备做CVS或Amnio, 有
两个选择:
1)按以前的老办法, 在11-13周做first trimester (用Ultrasound 做NT 和
抽血测hcG 和PPAP-A), 再在15-17周做second trimester quad screening (
抽血测AFP, hcG,Estriol 和Inhibin-A)。然后根据你的年龄组估计出一个risk
factor ratio (比喻,几百分之几, 几千分之几或几万分之几等)。这样你能看到你
的risk factor ratio 和cutoff值差多少。再加上20周的大B超。
2) 比较新的方法是做non-cell DNA (抽血做maternity T21, Eharmony etc )
加上在15-16周抽血做AFP。再加上20周的大B超。
要求加上一个11-13周的NT但是她始终不给不同意, 说做了non-cell DNA 后NT
是没... 阅读全帖
s*******9
发帖数: 177
29
我们这个医院所有的OB 都不管 genetic screening测试, 都归专门的genetic
counselor的管。
会见了genetic counselor, 说如果先不准备做CVS或Amnio, 有两个选择:
1)按以前的老办法, 在11-13周做first trimester (用Ultrasound 做NT 和
抽血测hcG 和PPAP-A), 再在15-17周做second trimester quad screening (
抽血测AFP, hcG,Estriol 和Inhibin-A)。然后根据你的年龄组估计出一个risk
factor ratio (比喻,几百分之几, 几千分之几或几万分之几等)。这样你能看到你
的risk factor ratio 和cutoff值差多少。再加上20周的大B超。
2) 比较新的方法是做non-cell DNA (抽血做maternity T21, Eharmony etc )
加上在15-16周抽血做AFP。再加上20周的大B超。
要求加上一个11-13周的NT但是她始终不给不同意, 说做了non-cell DNA 后NT
是没... 阅读全帖
s********r
发帖数: 109
30
准备申请绿卡,希望增加审稿机会。
本人在Nat Genet, Plos Genet, NAR, Bioinformaticc 等杂志不同研究方向发表10+文
章。为Plos Genet, BMC Bioinformatics, Plos Computational Biology 等杂志审稿6
次。
站内联系。
谢谢!
a****e
发帖数: 150
31
给Statistical Genetics, PLoS One, Statistical Methods in Medical Research 等
杂志审过。
熟悉的领域: Statistical Genetics, Genetic Epidemiology, Bioinformatics,
Semiparametric Inference, Measurement Error, Survival Analysis
请站内联系可提供CV。谢谢!
s*******9
发帖数: 177
32
我们这个医院所有的OB 都不管 genetic screening测试, 都归专门的genetic
counselor的管。
会见了genetic counselor, 说如果先不准备做CVS或Amnio, 有两个选择:
1)按以前的老办法, 在11-13周做first trimester (用Ultrasound 做NT 和
抽血测hcG 和PPAP-A), 再在15-17周做second trimester quad screening (
抽血测AFP, hcG,Estriol 和Inhibin-A)。然后根据你的年龄组估计出一个risk
factor ratio (比喻,几百分之几, 几千分之几或几万分之几等)。这样你能看到你
的risk factor ratio 和cutoff值差多少。再加上20周的大B超。
2) 比较新的方法是做non-cell DNA (抽血做maternity T21, Eharmony etc )
加上在15-16周抽血做AFP。再加上20周的大B超。
要求加上一个11-13周的NT但是她始终不给不同意, 说做了non-cell DNA 后NT
是没... 阅读全帖
s*******9
发帖数: 177
33
我们这个医院所有的OB 都不管 genetic screening测试, 都归专门的genetic
counselor的管。
会见了genetic counselor, 说如果先不准备做CVS或Amnio, 有两个选择:
1)按以前的老办法, 在11-13周做first trimester (用Ultrasound 做NT 和
抽血测hcG 和PPAP-A), 再在15-17周做second trimester quad screening (
抽血测AFP, hcG,Estriol 和Inhibin-A)。然后根据你的年龄组估计出一个risk
factor ratio (比喻,几百分之几, 几千分之几或几万分之几等)。这样你能看到你
的risk factor ratio 和cutoff值差多少。再加上20周的大B超。
2) 比较新的方法是做non-cell DNA (抽血做maternity T21, Eharmony etc )
加上在15-16周抽血做AFP。再加上20周的大B超。
要求加上一个11-13周的NT但是她始终不给不同意, 说做了non-cell DNA 后NT
是没... 阅读全帖
s*******9
发帖数: 177
34
我们这个医院所有的OB 都不管 genetic screening测试, 都归专门的genetic
counselor的管。
会见了genetic counselor, 说如果先不准备做CVS或Amnio, 有两个选择:
1)按以前的老办法, 在11-13周做first trimester (用Ultrasound 做NT 和
抽血测hcG 和PPAP-A), 再在15-17周做second trimester quad screening (
抽血测AFP, hcG,Estriol 和Inhibin-A)。然后根据你的年龄组估计出一个risk
factor ratio (比喻,几百分之几, 几千分之几或几万分之几等)。这样你能看到你
的risk factor ratio 和cutoff值差多少。再加上20周的大B超。
2) 比较新的方法是做cell-free DNA (抽血做maternity T21, harmony etc )
加上在15-16周抽血做AFP。再加上20周的大B超。
要求加上一个11-13周的NT但是她始终不给不同意, 说做了non-cell DNA 后NT
是没... 阅读全帖
D*****r
发帖数: 6791
35
Stephen C Stearns在耶鲁的进化论与生态学课程的第6讲
http://www.youtube.com/watch?v=ZzkLYZCzHXk
The Origin and Maintenance of Genetic Variation
Overview:
Mutations are the origin of genetic diversity. Mutations introduce new
traits, while selection eliminates most of the reproductively unsuccessful
traits. Sexual recombination of alleles can also account for much of the
genetic diversity in sexual species. In some instances, population size can
affect diversity and rates of evolution and fixation, but in other ca... 阅读全帖
b********d
发帖数: 5
36
The Section on Statistical Genetics in the Department of Biostatistics at
the University of Alabama at Birmingham is accepting applications from
statistical and other scientists for postdoctoral positions in Statistical
Genetics, Genetic Epidemiology, and/or Bioinformatics. Starting dates are
open and flexible. Salary is commensurate with qualifications but in all
cases equals or exceeds NIH post-doctoral stipends. No citizenship
requirement. For more information, please refer to http://www.soph
S***n
发帖数: 102
37
Genetically Engineered Plants and Foods: A Scientist's Analysis of the
Issues (Part I)
Peggy G. Lemaux
Annual Review of Plant Biology, Vol. 59: 771-812, 2008
Summary
1. 2.2. Except GMO crops, does genetic engineering play a role in
producing food? Please give 2 examples.
Genetic engineering certainly plays a role in food production, even with the
exception of GMO crops. Some organisms are modified through rDNA methods in
order to produce desirable enzymes used in food processing. An example o
c**i
发帖数: 6973
38
Karen Kaplan, Genetically modified cotton stops one bug but fosters others;
A Chinese crop designed to thrive without pesticides needs them again. Los
Angeles Times, May 16, 2010.
http://www.latimes.com/news/nationworld/nation/la-sci-cotton-bugs-20100516,0,2796333.story
("in 1997 [] genetically modified cotton was approved for use in China. * *
* Today, 95% of the cotton grown in China is genetically engineered")
Note:
(a) "A bollworm is a common term for any larva of a moth that attacks the
fru
c**i
发帖数: 6973
39
来自主题: Biology版 - Genetics of Tibetans (转载)
【 以下文字转载自 ChinaNews 讨论区 】
发信人: choi (choi), 信区: ChinaNews
标 题: Genetics of Tibetans
发信站: BBS 未名空间站 (Thu Jul 1 16:11:31 2010, 美东)
Shai Oster, Tibetans Had ‘Fastest Genetic Change Ever’ in Humans. China
Real Time (a brand of Wall Street Journal), July 2, 2010.
http://blogs.wsj.com/chinarealtime/2010/07/02/tibetans-had-fastest-genetic-change-ever-in-humans/
My comment: The abstract of article:
Yi X et al, Sequencing of 50 Human Exomes Reveals Adaptation to High
Altitude. Science, 329: 75 (July 2,
r**********e
发帖数: 587
40
来自主题: Biology版 - Journal "Genetics"
Thanks. I think my point is about population genetics, which a very special
field, with many computations and mathmatics.
Anyone who works on population genetics/ statistical genetics can give some
comments?
Thanks
g**********t
发帖数: 475
41
genetics是个好杂志,你导师说的没错。不过国内都是看影响因子的,所以还是投plos
genetics比较好。感觉你做的这个东西挺有意思的,为何不试试更好的杂志?
v***r
发帖数: 1046
42
For Experimental evolution , PLOS Genetics should be a better choice than
Genetics.
Why not trying Nature, Science, PNAS, NG, PLOS Bio?

SCI
l*******8
发帖数: 1745
43
我还真不清楚phd再做medical genetics后的就业情况:(。
我知道儿科三年住院医结束后,做medical genetics fellowship的人很少,主要是出
来后很难找到工作,两年fellow做完后,再回去做儿科的primary care,那就划不来了
。其实medical genetics specialist到最后就成了那些有先天疾病的儿科病人的
primary care医生。
P*********i
发帖数: 98
44
【 以下文字转载自 Immigration 讨论区 】
发信人: PandaFeifei (飞飞), 信区: Immigration
标 题: 求审稿机会:chemical biology, genetics, microbiology
关键字: chemical biology genetics microbiology
发信站: BBS 未名空间站 (Tue Jan 31 19:41:20 2012, 美东)
求chemical biology, genetics, microbiology的审稿机会
不胜感谢~
T****i
发帖数: 15191
45
来自主题: Biology版 - 好的和差的genetic screen
好的genetic screen,并不一定说工作量很小,都是
selection, 那有点勉为其难。而是说得到的gene要有功能相关性,最好在一个pathway
,这才说明你的design 很tight, 对后续的研究而言,你也知道在什么方向上。不好的
genetic screen,比如很多人做ENU-induced mutagenesis,然后看老鼠是不是shaky,
等等,你找到的基因可能功能上差者十万八千里。这样做,和偶然发现spontaneous
mutation没什么区别,只不过在时间上更集中而已。所以,phenotypes are not
created equal。好的phenotype (或reporter) 是好的genetic screen 的最重要要素
之一。
i*e
发帖数: 352
46
这个也不好比较吧
HMG名字就说明关注human的
Genetics和PLoS Genetics都不是限定在human
HMG和PLoS Genetics的话也许不少人先试着投后者
i*e
发帖数: 352
47
这个也不好比较吧
HMG名字就说明关注human的
Genetics和PLoS Genetics都不是限定在human
HMG和PLoS Genetics的话也许不少人先试着投后者
c********r
发帖数: 1125
48
embo j 算老牌杂志吧,尽管跟pnas一样因子下跌,认可度还是很高的。
plos genetics这两年上升势头很猛,因子貌似已经过了10了。。但是很多人还是没有
那么认可它的。我还记得几年前我们实验室的一篇文章是被development直接据掉。。
老板说就试试plos genetics吧,结果很顺利接受了。。。从此plos genetics在我心目
中的地位就。。。当然过了好几年了,情况变了。。。。
P*********y
发帖数: 41
49
来自主题: Biology版 - BGI Hunts for Genetic Links to High IQ
BGI Hunts for Genetic Links to High IQ
The Wall Street Journal reports that China's BGI is sequencing around 2,200
samples of individuals with high IQ in order to identify genes associated
with intelligence.
The project is sequencing the genomes of people with IQs of 160 or higher.
As the WSJ notes, "the average Nobel laureate registers at around 145."
These genomes will be compared with sequences from the general population in
the hope of identifying genes linked to high IQ. The scientists expe... 阅读全帖
w****s
发帖数: 122
50
PhD in statistical genetics and genetics epidemiology, currently a post-doc
at UCSF.
expertise: genome-wide association studies, disease heritability estimation,
population stratification and candidate-gene based/genome-wide association
analysis, admixture mapping,Meta-analysis of GWAS,confounding and
heterogeneity in GWAS
Thanks!!!
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