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发帖数: 524 | 1 【 以下文字转载自 Military 讨论区 】
发信人: dayuguanshui (大禹灌水), 信区: Military
标 题: 基因认为我是自由派 不是保守派
发信站: BBS 未名空间站 (Sat Feb 3 09:53:44 2018, 美东)
We did find a significant association between political conservatism and
rs10952668 (Table 5). This SNP lies in LOC642355, a pseudogene on chromosome
7. Not surprisingly, the SNP also showed an association with the highly
correlated trait of Democrat versus Republican (b=0.260, P<
.02).
An interesting finding was that the SNP associated with political
conservatism, rs10952668, also showed marginal evidence for association with
the personality traits openness (b=0.142, P<.06) and
agreeableness (b=0.130, P <.08), which are positively
correlated with political liberalism.68 Because the correlation is positive,
contrary to findings from political psychology that conservatives tend to
be less open and agreeable (in the sense of compassionate69), these results
raise the possibility that the association between rs10952668 and
conservatism may be attributable to selection bias rather than the gene
causing the personality traits typical of conservatives. (Because to our
knowledge this potential selection artifact has not been discussed in the
genetic epidemiology literature—although it has parallels in the effects of
natural selection on linkage disequilibrium—we explore it at some length
in the Discussion section.) After we added general cognitive ability,
openness, neuroticism, and agreeableness as covariates in an attempt to
control for selection bias, the association of rs10952668 and conservatism
diminished and fell short of significance.
基因详情
参考文献
位点：rs10952668 基因名：
CC 1362 人
自由派
TT 591 人
保守派
CT 1753 人
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