m***T 发帖数: 11058 | 1 Board&Wards says normal PT/PTT. FA and Kaplan both indicate prolonged PTT.
From what I can think, VWD mainly affects bleeding time due to abnormal
platelet adherence. However, vWF also protects VIII in blood. In VWD, due to
low level of VIII, PTT should be prolonged.
Am I correct?
Thanks | s**********r 发帖数: 178 | | n***a 发帖数: 1373 | 3 Your concept is right. But I remember that Goljan said in his audio that VWD
pateints sometimes have normal PTT. Ristocetin test is best for VWD. So I
think it depends. | d*******e 发帖数: 89 | 4 The concept is correct here, however, only around 30% patients with VWD have
prolonged aPTT. | d*******e 发帖数: 89 | 5 The concept is correct here, however, only around 30% patients with VWD have
prolonged aPTT. | m***T 发帖数: 11058 | 6 Thanks Guys for the info. |
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