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全部话题 - 话题: 20473
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B****i
发帖数: 466
1
来自主题: Military版 - 方舟子的2013年终总结
方舟子2013年十大要闻:
http://www.2250s.com/read.php?2-20473-20473
M*******n
发帖数: 10087
2
来自主题: SanFrancisco版 - 裤破体露117万能买这样的房子?
3152平方英尺(约300平方米),占地20473平方英尺,5房3浴3车库,建于1967年
http://www.wenxuecity.com/news/2014/10/03/3657933.html
c********n
发帖数: 225
3
2016年8月24日
业界大规模重复验证NgAgo基因编辑功能,而不得其果的经历,
可能会带来对于“重复” (replication)实验数据发表方式的革新:
《自然》杂志 2016年8月24日 Editorial
http://www.nature.com/news/go-forth-and-replicate-1.20473
Go forth and replicate!
“To make replication studies more useful, researchers must make more of
them, funders must encourage them and journals must publish them.”
“To foster better behaviour, replication attempts must become more common.
We urge researchers to open their file drawers. We urge authors to cooperate
with reasonable req... 阅读全帖

发帖数: 1
4
自然 http://www.nature.com/news/go-forth-and-replicate-1.20473
To foster better behaviour, replication attempts must become more common. We
urge researchers to open their file drawers. We urge authors to cooperate
with reasonable requests for primary data, to assume good intent and to
write papers — and keep records — assuming that others will want to
replicate their work. We urge funders and publishers to support tools that
help researchers to thread the literature together. We welcome, and will ... 阅读全帖
c********n
发帖数: 225
5
2016年8月24日
业界大规模重复验证NgAgo基因编辑功能,而不得其果的经历,
可能会带来对于“重复” (replication)实验数据发表方式的革新:
《自然》杂志 2016年8月24日 Editorial
http://www.nature.com/news/go-forth-and-replicate-1.20473
Go forth and replicate!
“To make replication studies more useful, researchers must make more of
them, funders must encourage them and journals must publish them.”
“To foster better behaviour, replication attempts must become more common.
We urge researchers to open their file drawers. We urge authors to cooperate
with reasonable req... 阅读全帖

发帖数: 1
6
自然 http://www.nature.com/news/go-forth-and-replicate-1.20473
To foster better behaviour, replication attempts must become more common. We
urge researchers to open their file drawers. We urge authors to cooperate
with reasonable requests for primary data, to assume good intent and to
write papers — and keep records — assuming that others will want to
replicate their work. We urge funders and publishers to support tools that
help researchers to thread the literature together. We welcome, and will ... 阅读全帖
c********n
发帖数: 225
7
来自主题: Biology版 - 火锅哥请注意了(转)
截止到2016年8月24日
【记录历史】谁重复验证了NgAgo?
收集到3则“重复实验证实韩春雨组NgAgo基因编辑功能”的信息,
实例详细信息请参见:
http://www.mitbbs.com/article_t/Biology/32034437.html
其中:
- 1则出自“火锅哥”
o 发布人“做的中间发现了一个问题,才发现韩点播的很有道理”,实验“调整了
步骤,这在韩的paper里没有提”, 实验结果“关键是测序也和韩的报道能温和”
o 发布人许诺2016年7月22日前发布重复结果到BioRxiv
o 截止到2016年8月24日,仍无发布消息
原文链接
http://www.mitbbs.com/article_t/Biology/32028091.html
鉴于"科学的事情要由科学来解决”
http://mt.sohu.com/20160801/n462050233.shtml
以及有可能在Nature杂志上发表关于Replication实验数据的文章,
http://www.nature.com/news/go-forth-and-replicate-... 阅读全帖
c********n
发帖数: 225
8
2016年8月24日
业界大规模重复验证NgAgo基因编辑功能,而不得其果的经历,
可能会带来对于“重复” (replication)实验数据发表方式的革新:
《自然》杂志 2016年8月24日 Editorial
http://www.nature.com/news/go-forth-and-replicate-1.20473
Go forth and replicate!
“To make replication studies more useful, researchers must make more of
them, funders must encourage them and journals must publish them.”
“To foster better behaviour, replication attempts must become more common.
We urge researchers to open their file drawers. We urge authors to cooperate
with reasonable req... 阅读全帖
c********n
发帖数: 225
9
Date:2016年08月22日
(NBT paper 上线三个多月以后)
(韩春雨Addgene 更新protocol 两个星期以后)
Title:NgAgo你做出来了吗?
Link:
http://blog.sciencenet.cn/blog-851798-997067.html
Key Points:
-在follow NBT原始protocol 无法重复验证NgAgo基因编辑功能之后,作者追加实验,
用Addgene更新的protocol,再次无法重复验证NgAgo基因编辑功能。对照组CRISPR/
Cas9,2/2 成功率。
Date:2016年08月24日(NBT paper 上线三个多月以后)
Title:Go forth and replicate!
Link:
http://www.nature.com/news/go-forth-and-replicate-1.20473
Key Points:
编者注:业界大规模重复验证NgAgo基因编辑功能,而不得其果的经历,
可能会带来对于“重复” (replication)实验数据发表方式的革新。
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