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全部话题 - 话题: metabolomics
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j*********1
发帖数: 109
1
本人在这个组,刚刚group发布了beta版本。有兴趣的可以试着用用。说是用于
metabolomics,其实对LC-MS的数据普遍可用,需要upload 两组data进行对比分析。
Announcement:如下
The Scripps Center for Metabolomics is pleased to announce XCMS Online, a
new user-friendly approach to process metabolomics data.
XCMS Online provides the same high-quality metabolomic analysis that you are
used to but in a user-friendly, web-based format. XCMS Online allows users
to easily upload LC/MS metabolomic data that can then be processed with a
few simple mouse clicks. Predefi... 阅读全帖
j*********1
发帖数: 109
2
本人在这个组,刚刚group发布了beta版本。有兴趣的可以试着用用。说是用于
metabolomics,其实对LC-MS的数据普遍可用,需要upload 两组data进行对比分析。
Announcement:如下
The Scripps Center for Metabolomics is pleased to announce XCMS Online, a
new user-friendly approach to process metabolomics data.
XCMS Online provides the same high-quality metabolomic analysis that you are
used to but in a user-friendly, web-based format. XCMS Online allows users
to easily upload LC/MS metabolomic data that can then be processed with a
few simple mouse clicks. Predefin... 阅读全帖
j*********1
发帖数: 109
3
本人在这个组,刚刚group发布了beta版本。有兴趣的可以试着用用。说是用于
metabolomics,其实对LC-MS的数据普遍可用,需要upload 两组data进行对比分析。
Announcement:如下
Announcement:
The Scripps Center for Metabolomics is pleased to announce XCMS Online, a
new user-friendly approach to process metabolomics data.
XCMS Online provides the same high-quality metabolomic analysis that you are
used to but in a user-friendly, web-based format. XCMS Online allows users
to easily upload LC/MS metabolomic data that can then be processed with a
few simple mouse cl... 阅读全帖
G***G
发帖数: 16778
4
来自主题: Biology版 - metabolome的重音
【 以下文字转载自 Faculty 讨论区 】
发信人: GoooG (pumpkin), 信区: Faculty
标 题: metabolome的重音
发信站: BBS 未名空间站 (Wed Apr 12 10:30:53 2017, 美东)
where is the stressed syllable for metabolome?
and same question for transcriptome, metabolomic, metabolomics?
G***G
发帖数: 16778
5
来自主题: Faculty版 - metabolome的重音
where is the stressed syllable for metabolome?
and same question for transcriptome, metabolomic, metabolomics?
f*********e
发帖数: 1144
6
my feeling is the other way around, the bottle-neck is lacking of
biochemistry knowledge to interpret hundreds of differential expression
metabolites into a biological sense
A more ambitious idea, we need a great biologist to reconstruct the
disconnected information between proteomics and metabolomics, correlating
alterations occured on signaling pathway and metabolomics pathway

and
h*****s
发帖数: 153
7
【 以下文字转载自 Chemistry 讨论区 】
发信人: higness (higness), 信区: Chemistry
标 题: Lipidomics 和 metabolomics 是好坑吗?
发信站: BBS 未名空间站 (Mon Nov 7 03:09:33 2011, 美东)
老板最近很想让我插omics的坑,因为我本科是化学和分子生物双学位。他本人是搞电
化学,MS,计量学的。我有个副导师是数学系的做统计算法,EE信号处理和金融模型研究的,如果走omics的路
的话基本就是分析化学+数学统计的研究模式。都说生物是火坑,外加老板不是内行,
这条路能走吗?
a***y
发帖数: 19743
8
要做metabolomics必须要有做wet lab的合作者吧
h*****s
发帖数: 153
9

展开讲讲?现在metabolomics基本上都是用MS做的,NMR很少,所以老板觉得这是个好
的突入口。
K******S
发帖数: 10109
10
re,
in addition, IMHO, the major road-block for biology ppl to do lipidomics and
metabolomics is the chemistry knowledge, especially in the late data
analysis stage.
h*****s
发帖数: 153
11

I think that is where to apply statistical mode to discriminate molecules.
There is a metabolomics group in Imperial College Medicine School, they did
a lot chemometrics and NMR research on metabolomcs, quite famous in our
analytical chemistry filed.
g*********3
发帖数: 177
12
I don't know too much about the sensitivity of NMR. Actually MS sensity is
not good enough for many projects including mine. I was told the best MS was
around 20 attomolar.
How about NMR?
Another question: I guess for both NMR and MS in Metabolomics, it is not
widely used to characterize all the metabolites information in the sample. (
in contrast to microarray)
I read some paper and they always have a list of candidates to measure.
How long is the list of metabolites now?
Thanks.
b*******g
发帖数: 1309
13
广告一下吧
我们的database 有超过42000个化合物的数据
The METLIN Metabolite Database is a repository of metabolite information as
well as tandem mass spectrometry data.
METLIN is a metabolite database for metabolomics containing over 42,000
structures
http://metlin.scripps.edu/

microarray数据里早就剃掉了
w***e
发帖数: 269
14
来自主题: Biology版 - DuPont 招 intern 做 metabolomics
很少有生物出身的人做metabolomics的。都是化学的人在做,可以转到化学版去。
B8
发帖数: 92
15
The Department of Environmental Sciences and Engineering at Gillings School
of GlobalPublic Health, University of North Carolina at Chapel Hill has a
postdoc opening. We are looking for a self-motivated postdoc to conduct
omics profiling to understand the interactions between the gut microbiome
and diseases/environmental exposures. Our lab has dedicated high-end mass
spectrometers, including Q-Exactive HF Orbitrap and 6550 Q-TOF.
A PhD degree or solid training in analytical chemistry, proteomics... 阅读全帖
t*****z
发帖数: 1598
16
来自主题: Biology版 - metabolome的重音
不客气。这是我听过N多次的metabolome大佬和他的小弟们的发音。
G*****h
发帖数: 320
17
希望在这里找一两个有 metabolomics 经验的审稿人。
有意者请发邮件给我,简单介绍一下学历、工作、文章(或简历)。
如果被邀请,请一定认真完成 review。能够及时最好,但晚几天问题不大。之前碰见
过得了邀请函,但没有递交评审意见的。
因为每次问询的人不少,所以请原谅我不一定回信每位来信的朋友。
c******m
发帖数: 884
18
Thank you for sharing. I am using AB 4000QTrap for metabolomic studies. All
my file is ".wiff" from Analyst. Is it compatible on XCMS online? Thanks.

are
users
R****n
发帖数: 708
19
【 以下文字转载自 Biology 讨论区 】
发信人: RinMan (Walk with the Earth Mother.), 信区: Biology
标 题: 做high-throughput metabolomics和proteiomics的Mass Spec选择
发信站: BBS 未名空间站 (Wed Nov 23 11:56:39 2016, 美东)
系里准备进一台,原来有两台Agilent Q-TOF和QQQ.LC是1100系列,机器有点老了,毛
病多。做高通量,那个组合sensitivity和resolution比较好,再一个比较easy
maintainance。多谢!
g*****x
发帖数: 3283
20
做proteomics直接上qexactive
metabolomics上sciex的qqq吧
I******t
发帖数: 1619
21
来自主题: Pharmaceutical版 - 有人在做metabolomics吗?
NMR就可以准确定性啊,定量差点,灵敏度差,不过基本MS的metabolomics的数据库也
有啊,好几个啊,而且有NIST library可以来search GCMS的数据啊,对于一些比较低
浓度的化合物来说,确实是比较难,不过现在的分析手段,越来越好了,LECO的那个
GCXGC MS好像很强大啊,软件也很棒哦

't
c******m
发帖数: 884
22
现在会做LCMS的也越来越多了。。。你如果是做postdoc,一两年以后出来也许还能找
。如果是准备选组的phd student,那5年以后谁都不知道行情会如何。。。
metabolism应用更广一些,不过现在职位都去了CRO。metabolomics一般只有大公司做
,而且现在招人也很少。。。

LC
c******m
发帖数: 884
23
现在会做LCMS的也越来越多了。。。你如果是做postdoc,一两年以后出来也许还能找
。如果是准备选组的phd student,那5年以后谁都不知道行情会如何。。。
metabolism应用更广一些,不过现在职位都去了CRO。metabolomics一般只有大公司做
,而且现在招人也很少。。。

LC
U******m
发帖数: 423
24
来自主题: Pharmaceutical版 - 做metabolomics的好找工作吗?
有药物分析背景,做metabolomics的,请问好找工作吗?
w******e
发帖数: 953
25
How safe does transgenic food need to be?
Laura DeFrancesco1
Journal name:
Nature Biotechnology
Volume:
31,
Pages:
794–802
Year published:
(2013)
DOI:
doi:10.1038/nbt.2686
Published online 10 September 2013 Corrected online 26 September 2013
Article tools
PDF
How safe does transgenic food need to be?
Download as PDF (812 KB) View interactive PDF in ReadCube
Citation
Reprints
Rights & permissions
Article metrics
Disputes over how to assess a foodstuff's safety continue to play into
public fears a... 阅读全帖
m*******s
发帖数: 469
26
Let me know if you believe you are qualified.
________________________________________
Corporate Overview
Metabolon is a diagnostics and services company offering the industry's
leading biochemical profiling platform. Our patented platform provides a
global analysis of complex biological samples for the discovery of
markers and pathways associated with drug action and disease. This
metabolomics-driven approach enables the identification of biomarkers
useful for the development of a wide range of... 阅读全帖
k*****m
发帖数: 5
27
来自主题: Postdoc版 - Postdoctoral opportunity at UCSD
Postdoctoral opportunity at UCSD:
I am helping my former mentor look for a postdoc. Please send your
application directly to Professor Naviaux.
Here's the job posting:
The Naviaux Lab at the University of California, San Diego has an immediate
opening for a postdoc (MD, PhD, or both) with broad experience in the mass
spectrometry of small molecules and metabolomics. Specific experience with
the quantitative analysis of organic acids, amino acids, nucleotides, thiol
compounds, neurotransmitters, ... 阅读全帖
p*******r
发帖数: 4048
28
顺便说一句,因为陈的关系,国内现在这类研究也极容易拿钱。不过好的东西出来得还
不多, 主要是能全proteome, metabolome观测的技术还不够好。
你可以去查metabolomics & Chinese Medicine.
l******0
发帖数: 12
29
I will have some manuscripts for review in the end of April 2011. These
manuscripts are in the filed of LC-MS based proteomics or metabolomics.
If interested, please send your basic contact information along with a list
of selected publications to m***********[email protected]
Only candidates with strong background in proteomics or metabolomics will be
considered and contacted.
Thank you very much for your interest in advance.
k*****m
发帖数: 5
30
来自主题: Biology版 - Postdoctoral opportunity at UCSD
Postdoctoral opportunity at UCSD:
I am helping my former mentor look for a postdoc. Please send your
application directly to Professor Naviaux.
Here's the job posting:
The Naviaux Lab at the University of California, San Diego has an immediate
opening for a postdoc (MD, PhD, or both) with broad experience in the mass
spectrometry of small molecules and metabolomics. Specific experience with
the quantitative analysis of organic acids, amino acids, nucleotides, thiol
compounds, neurotransmitters, ... 阅读全帖
t********e
发帖数: 107
31
来自主题: Chemistry版 - Papers! Please Help !!!!
1. Mass Spectrometry-Based Metabolomics of Yeast, 2010, Joshua Rabinowitz
2. Hydrophilic interaction chromatography coupled to MS for metabonomic/
metabolomic studies, 2010, Ian D. Wilson,Journal of Separation Science
3. Hydrophilic stationary phases: A practical approach for the co-analysis
of compounds with varying polarity in biological matrices,2010,
E. Goucher,Journal of Separation Science.
4. Dual hydrophilic interaction-RP retention mechanism on polar columns:
Structural correlations and
l******0
发帖数: 12
32
I will have some manuscripts for review in the end of April 2011. These
manuscripts are in the filed of LC-MS based proteomics or metabolomics.
If interested, please send your basic contact information along with a list
of selected publications to m***********[email protected]
Only candidates with strong background in proteomics or metabolomics will be
considered and contacted.
Thank you very much for your interest in advance.
k*****m
发帖数: 5
33
来自主题: Chemistry版 - Postdoctoral opportunity at UCSD
Postdoctoral opportunity at UCSD:
I am helping my former mentor look for a postdoc. Please send your application directly to Professor Naviaux.
Here's the job posting:
The Naviaux Lab at the University of California, San Diego has an immediate
opening for a postdoc (MD, PhD, or both) with broad experience in the mass
spectrometry of small molecules and metabolomics. Specific experience with
the quantitative analysis of organic acids, amino acids, nucleotides, thiol
compounds, neurotransmitters, ... 阅读全帖
b*******h
发帖数: 35
34
诚求审稿机会:分析方向 bioanalysis, metabolomics, proteomics, liquid
chromatography-mass spectrometry, instrumentation.
Expertise in the mechanism, instrumentation, and application of MS, tandem
MS, and ion mobility spectrometry; especially in traditional and novel
ionization methods.
Currently focusing on LC-MS based untargeted metabolomics study, involving
column packing, testing, and ultra ultra high pressure system building.
可通过站内信发简历,万分感谢!
t***b
发帖数: 3
35
来自主题: Pharmaceutical版 - 《关于专业的选择》
pk/pd相对metabolomics容易进industry,metabolomics在industry很少开展
I******t
发帖数: 1619
36
来自主题: Pharmaceutical版 - 哪个专业好点?
如果以后去学术界发展的话,是不是metabolomics要好些?
楼上也做metabolomics吗?
t*********1
发帖数: 2852
37
来自主题: Pharmaceutical版 - Two Job Openings
Please contact recruiter directly
Corey Shankle
Business Development
Accord Scientific, LLC
www.accordscientific.com
Cell – 615.330.6045
The first opportunity is a Scientist – Metabolomics located in Natick, MA,
and the second opportunity is a Research Scientist – Drug Metabolism
located in Memphis, TN.
The first opportunity requires a highly motivated individual with an
extensive background in metabolomics and small molecule analysis using LC/MS
/MS and GC/MS platforms.
The second opportunity r... 阅读全帖

发帖数: 1
38
来自主题: Classified版 - position available
Postdoc fellow / research scholar / exchange student positions are available
at Baylor College of Medicine at Houston, Texas. Studies are focused on
epigenomic regulation of metabolism and cognitive functions, involving
nuclear hormone receptors and gene expression regulation in diabetes, autism
, and circadian clock. We are interested in how hypothalamic circadian clock
regulates systemic glucose metabolism, and how physical exercise remodels
skeletal muscle bioenergetics. Approaches include ge... 阅读全帖
q******g
发帖数: 390
39
Abergel, Rebecca J., Lawrence Berkeley National Laboratory, Berkeley, CA, “
Harnessing f㎡rbital Bonding through Precision Antenna Ligand Design for
Actinide Complexation,” selected by the Office of Basic Energy Sciences.
Braley, Jenifer C., Colorado School of Mines, Golden, CO, “Actinide N〥onor
Thermodynamics: Expanding the f〦lement Covalency Dialogue,” selected by
the Office of Basic Energy Sciences.
Cerfon, Antoine J., New York University, New York, NY, “High Performance
Equilibrium Solvers fo... 阅读全帖
y******u
发帖数: 1123
40
来自主题: Faculty版 - 交叉学科找faculty还是工业界
metabolomics质谱好应该好进公司
B*H
发帖数: 2158
41
Bioinformatician Position in the Brunet Lab
An exciting opportunity is
available for a Bioinformatician in the Brunet lab in the Department of
Genetics at Stanford University http://stanford.edu/group/brunet. This
position offers the opportunity to conduct cutting-edge research on the
epigenetic regulation of aging and age-related diseases. The successful
candidate will have an opportunity to creatively come up with their own ways
to analyze primary large-scale data generated by the lab (RNA-s... 阅读全帖
l********l
发帖数: 8
42
Job description:
This position mainly focus on LC-MS-based metabolomics and its application
in xenobiotic metabolism, pharmacokinetics & drug-induced liver injury. The
candidates should have a PhD with chemistry background. Preference will be
given to those who have hand-on experience on UPLC-MS operation, method
development, maintenance, sample preparation, drug metabolism, and
metabolite identification using MS/MS. Animal handling of mice is also
required for this position. Training in pharmac... 阅读全帖
z********8
发帖数: 11
43
上海交通大学运动健康工程中心招聘青年研究员(tenure-track AP):运动生理
学、运动医学、运动与代谢组学、运动与基因组学、运动与蛋白组学、表观遗传学、内
分泌疾病预防、系统生物学、生物信息学、生物工程等相关领域;
 
基本要求:在以上相关领域发表过优秀的文章,3年以上的海外博士后或相关领域海外
工作经历(博士学位是国外授予的学位)或4年以上的海外博士后或相关领域海外工作
经历(博士学位是国内授予的学位)。
 
基本待遇:年薪13-21万; 30万安家费;12万科研启动经费。
 
具体的要求请看以下的英文职位信息,谢谢大家!我只是代发,请不要站内信联系我!
Exercise Health and Technology Center (EHTC) 
at Shanghai Jiao Tong University (SJTU) of&#
160;China invites applicati... 阅读全帖
z********8
发帖数: 11
44
Exercise Health and Technology Center (EHTC) at Shanghai Jiao Tong
University (SJTU) of China invites applications for Special Young Researcher
(tenure-track Assistant Professor) positions in relevant fields. EHTC is a
newly established interdisciplinary research institute at the main campus of
SJTU, in accordance with national "population health" initiatives. From the
perspective of exercise training and health promotion, EHTC takes advantage
of the expertise in medicine, biology, engineering a... 阅读全帖
z********8
发帖数: 11
45
来自主题: JobMarket版 - 上海交通大学青年研究员招聘
上海交通大学运动健康工程中心招聘青年研究员(tenure-track AP):运动生理学、
运动医学、运动与代谢组学、运动与基因组学、运动与蛋白组学、表观遗传学、内分泌
疾病预防、系统生物学、生物信息学、生物工程等相关领域;
基本要求:在以上相关领域发表过优秀的文章,3年以上的海外博士后或相关领域海外
工作经历(博士学位是国外授予的学位)或4年以上的海外博士后或相关领域海外工作
经历(博士学位是国内授予的学位)。
基本待遇:年薪13-21万RMB;30万RMB安家费;12万RMB科研启动经费。
具体的要求请看以下的英文职位信息,谢谢大家!我只是代发,请不要站内信联系我!
Exercise Health and Technology Center (EHTC) at Shanghai Jiao Tong
University (SJTU) of China invites applications for Special Young Researcher
(tenure-track Assistant Professor) positions in relevant fields. EH... 阅读全帖

发帖数: 1
46
来自主题: JobMarket版 - position available
Postdoc fellow / research scholar / exchange student positions are available
at Baylor College of Medicine at Houston, Texas. Studies are focused on
epigenomic regulation of metabolism and cognitive functions, involving
nuclear hormone receptors and gene expression regulation in diabetes, autism
, and circadian clock. We are interested in how hypothalamic circadian clock
regulates systemic glucose metabolism, and how physical exercise remodels
skeletal muscle bioenergetics. Approaches include ge... 阅读全帖
h****k
发帖数: 1
47
Postdoctoral Position in Bioinformatics and Computational Biology
Description
Applications are invited for postdoctoral positions to work on mass spectrometry-based computational
metabolomics/proteomics and the integration and modeling of –omics data. The successful candidate is
expected to identify and formulate new mathematical problems and to apply applied mathematics,
statistics, and machine learning to designing novel algorithms. This project is an integral part of our long
term goal to dev
m******o
发帖数: 9
48
来自主题: Postdoc版 - 帮我看看这个是口头offer吗
本人土博,电话面试过一美国实验室,收到回复如下。这个是不是口头offer?
Dear xxxx,
I did hear from xxx, thanks. All is fine. I will make you an offer very
shortly, but I busy right now in xxxx, learning some metabolomics to go with
your genetics….
Back to you very soon.
xxxxx
f*********a
发帖数: 46
49
A postdoctoral position, starting January 2016, is available in a newly
established laboratory in the Department of Integrative Biology and
Physiology at University of Minnesota. The research in the laboratory is
centered on understanding how metabolic homeostasis is maintained at the
physiological level and defining the pathological alterations in metabolic
diseases, including obesity, diabetes, digestive diseases, and inflammation.
We are interested in defining molecular mechanisms by which ho... 阅读全帖

发帖数: 1
50
您好, 为您方便阅读先简要描述下:
1) Published 40 papers (IF 2.6-5) in 23 journals and Authorized 2 patents in
China;
2) Served as Reviewer for 3 journals like Journal of Pharmaceutical and
Biomedical Analysis, Journal of Ethnopharmacology,Phytomedicine;
3) more than 16 conference posters or talks.
4) serve as Editor-in-Chief for Journal of Allergy and Asthma Reports
随时可提供简历。
如您有相关审稿机会请email [email protected] 或 [email protected] 或站内私信。
非常感谢。
祝好
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