g*********5
发帖数: 2533 | 1 Introduction:
Cells that simultaneously secrete and sense the same signaling molecule are
ubiquitous. Bacteria sense a quorum by secreting and sensing an autoinducer;
T cells induce a monoclonal
immune response by secreting and sensing a cytokine; and epithelial cells
can become cancerous through misregulated secreting and sensing of a growth
factor. Many of these cells use the same core signaling-circuit motif to
realize a diverse repertoire of biological functions. The full range of
functions ... 阅读全帖 |
|
m***T
发帖数: 11058 | 2 sequencing市场更热闹了。
http://www.genomeweb.com//node/1396761?utm_source=SilverpopMail
Roche Acquires Nanopore Sequencing Firm Genia Technologies for up to $350M
NEW YORK (GenomeWeb) – Roche said today that it will acquire Genia
Technologies for $125 million in cash and up to $225 million in additional
payments tied to milestones. Once the deal closes, Genia will be integrated
into the Roche Sequencing Unit.
Genia, based in Mountain View, Calif., has been developing a single-molecule
sequencing-by-sy... 阅读全帖 |
|
x****s
发帖数: 29 | 3 I think it means the pathway is not working normally as it is supposed to be
. In normal cells, numerous cellular pathways are being precisely regulated
to ensure a normal functional output. However, in the case of cancer, the
situation of pathways is usually found quite different. For example, p53
inactivation is frequently observed in many cancer types. This molecule is
critical in DNA repair, cell cycle as well as apoptosis of host cells.
Therefore, abnormality of this molecule would cause an... 阅读全帖 |
|
L*****C
发帖数: 157 | 4 A prominent biochemist and his co-author are pulling one of their papers in
the Journal of Biological Chemistry because…well, we’re not sure.
That’s because the retraction note is – as we’ve come to expect from JBC
– not very informative.
Here’s the only explanation for the retraction of “The Down Syndrome Cell
Adhesion Molecule (DSCAM) Interacts with and Activates Pak”:
This article has been withdrawn by the authors.
The corresponding author, Kun-Liang Guan, earned a MacArthur “genius”
grant in... 阅读全帖 |
|
K**4
发帖数: 1015 | 5 I didnt read the paper but from what you have said, it is impossible that
small molecule kinase can catalyze proteins.If it is indeed a small molecule
kinase, and his paper showed it is protein kinase, I think he definitely
manipulated the data.
Sorry I dont have Chinese input right now.
kinase |
|
K**4
发帖数: 1015 | 6 Indeed PKM2 is a small molecule kinase, and its catalytic site can not
accumulate a protein like a protein kinase. This is very likely another
faked Cell paper.
molecule |
|
发帖数: 1 | 7 Methods Mol Biol. 2016;1434:153-67. doi: 10.1007/978-1-4939-3652-6_11.
Protocols for Exosome Isolation and RNA Profiling.
Marqués-García F1,2, Isidoro-García M3,4,5.
Author information
Abstract
Exosomes are small extracellular vesicles of multivesicular bodies derived
from the cell endosome. Molecules have a characteristic composition both in
the membrane and in the carried load. These particles are located in the
culture medium of cells in vitro and in vivo body fluids, being synthesized
by alm... 阅读全帖 |
|
发帖数: 1 | 8 When will your statistic data collection be completed? Let's talk about the
success
rate then.
Your comments are so interesting. If you do not know the science, just be
patient and wait for more answers.
{1) Do you understand statistics?}
-----------------------------------
Ok, alright. I spent some time to explain it to you.
Fig 4a, the band distance from 1000 to 250 is 2.5 cm on my monitor. Based on
linear regression of Log(size) and migration distance, 30 nt will give out
1.3 mm difference ar... 阅读全帖 |
|
n**********g
发帖数: 196 | 9 1) The current low (zero) verified success rate is sufficient for people to
question the story.
When will your statistic data collection be completed? Let's talk about the
success
rate then.
Your comments are so interesting. If you do not know the science, just be
patient and wait for more answers.
2) “Do you think 1.3 mm difference (resolution)
can be achieved on peaks with a width of 1.5-2 mm?” The answer is yes
because of Fig 4e. Your statement is “difference
sample preparation” is completely... 阅读全帖 |
|
l*****7
发帖数: 8463 | 10 The rods and cones of the retina in the eye.
The rods are sensitive to low light intensity
The cones are sensitive to high light intensity
When light enters the eye, it comes in contact with the photosensitive
chemical rhodopsin (also called visual purple). Rhodopsin is a mixture of a
protein called scotopsin and 11-cis-retinal -- the latter is derived from
vitamin A (which is why a lack of vitamin A causes vision problems).
Rhodopsin decomposes when it is exposed to light because light causes a... 阅读全帖 |
|
l*******1
发帖数: 16217 | 11 看你们这二道贩子文章 不如看底下英文UC伯克利是怎么耍臭不要脸的
专利局都说了张峰的专利在真核生物中有效 是一个separate case
UC 伯克利还在那意淫要所有细胞类型中的专利 你让美国专利局自己抽自己的脸吗
Appeals board clears way for UC Berkeley to receive patent on CRISPR-Cas9
gene editing
By Robert Sanders, Media relations | FEBRUARY 15, 2017
Click to share on Twitter (Opens in new window)181Click to share on Facebook
(Opens in new window)181Click to share on Google+ (Opens in new window)
Click to share on Reddit (Opens in new window)Click to email this to a
friend (Opens in new window)... 阅读全帖 |
|
j**h
发帖数: 126 | 12 nature.com
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Nature
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Volume 544
Issue 7648
News
Article
NATURE | NEWS
Sharing
Compass protein attracts heap of criticism
Debate grows over a molecule implicated in animal navigation.
David Cyranoski
04 April 2017
Article tools
PDF
Rights & Permissions
George Grall/NGC
The red-spotted newt and many other animals can somehow sense Earth’s
magnetic field.
For decades, scientists have wondered how animals c... 阅读全帖 |
|
S*****a
发帖数: 63 | 13 【 以下文字转载自 Pharmaceutical 讨论区 】
发信人: Somalia (Anti-Pirates), 信区: Pharmaceutical
标 题: Biologics Discovery and Development Positions Available at Abpro Labs in Woburn, MA
关键字: Biologics,Discovery,Development,Antibody,Computational
发信站: BBS 未名空间站 (Wed May 31 20:28:52 2017, 美东)
Multiple Biologics Discovery and Development Positions Available at Abpro
Labs in Woburn, MA
www.abpro-labs.com
To apply please send resume to [email protected]
1. Scientist/Senior Scientist, Antibody Display Technology
... 阅读全帖 |
|
h*****a
发帖数: 1295 | 14 【 以下文字转载自 Faculty 讨论区 】
发信人: haibara (Haibara Ai), 信区: Faculty
标 题: DOE SBIR寻National Lab或者学校合作者
发信站: BBS 未名空间站 (Tue Aug 8 12:47:14 2017, 美东)
需要的方向:biological/enzymatic upgrading of 1C organic small molecules into
larger fuel molecules.
具体的DOE solicitation是DOE SBIR 18.1 Topic 16b.
https://science.energy.gov/sbir/funding-opportunities/
我这边可以做CO2 reduction，需要合作者能帮忙把还原产物升级。
Phase I的项目。站内联系。
谢谢！ |
|
s******y
发帖数: 17729 | 15 【 以下文字转载自 Military 讨论区 】
发信人: rbs (jay), 信区: Military
标 题: 诺委会太不像话了 (转载)
发信站: BBS 未名空间站 (Wed Oct 4 10:58:51 2017, 美东)
发信人: rbs (jay), 信区: Joke
标 题: 诺委会太不像话了
发信站: BBS 未名空间站 (Wed Oct 4 10:23:52 2017, 美东)
尼玛87篇参考文献就不能加一篇施教授或能教授的CNS？
References
1. Ruska, E., Nobel Lectures, Physics 1981-1990, Tore Frängsmyr and
Gösta Ekspong, Eds. (1993) World Scientific Publishing, Singapore
2. Marton, L. (1934) Electron microscopy of biological objects. Nature
133, 911-911
3. Althoff, T., Mi... 阅读全帖 |
|
m********8
发帖数: 314 | 16 这篇论文的提法是co-stimulatory molecule that may be involved in the negative
regulation of cell-mediated immune responses.能算作是“误认为PD-L1(B7-H1)是
抑制T细胞增殖”的论断吗？
https://www.nature.com/articles/nm1299_1365
摘要：The B7 family members B7-1 and B7-2 interact with CD28 and constitute
an essential T-cell co-stimulatory pathway in the initiation of antigen-
specific humoral and cell-mediated immune response. Here, we describe a
third member of the B7 family, called B7-H1 that does not bind CD28,
cytotoxic T-lymphoc... 阅读全帖 |
|
q******s
发帖数: 7 | 17 郑上游教授目前在新加坡南洋理工大学任教，就职于物理及应用物理系。从2012年1月
开始，他的课题组有两个博士生名额开始招收，希望有志于Soft Condensed Matter
Physics, Single Molecule Physics, Biophysics等方面研究的博士生申请他的科研组
。博士生会有全额的奖学金资助。有相关研究经历的博士后，也欢迎申请他的课题组。
此课题组有一个特别的交流计划，博班期间，博士生将去宾夕法尼亚大学或哈佛大学与
郑教授前老板进行3〜6月的研究。
南洋理工大学这些年在飞速进步, 特别是工程及物理学院, 科研已具有非常高的水平。
学校科研投入也很大。感兴趣的同学可以参看学校的网页: www.ntu.edu.sg (School
of Physical and Mathematical Sciences).
请感兴趣的同学直接跟郑教授联系，把简历发到他的邮箱：
s***[email protected]
Phone: (65)-6592-3148
Prof. Shang-You Tee (School of Physical and Mathema... 阅读全帖 |
|
r****o
发帖数: 104 | 18 A postdoc position in Missouri University of Science and Technology is open.
The successful candidate will conduct research on nano-channel imaging using
our single cell and single molecule imaging system to investigate fluid
flow behavior of different fluids and gases in tight formations during
hydraulic fracturing. The postdoctoral fellow will design the experiments,
carry out the experiments, collect data and analyze the data. The
postdoctoral fellow will write monthly report on the progres... 阅读全帖 |
|
w********h
发帖数: 12367 | 19 http://online.wsj.com/article/SB10001424052970204683204574358170813148330.html
KRZYSZTOF MATYJASZEWSKI, Professor, Department of Chemistry, Carnegie Mellon
University
Dr. Matyjaszewski developed atom transfer radical polymerization, or ATRP, a
way of combining small molecules called monomers into blocks of polymers,
which are plastics made up of long molecules. This method allows for the
production of a combination of materials with multiple properties that can
be controlled in ways that traditi |
|
|
D******n
发帖数: 2836 | 21 【 以下文字转载自 Biology 讨论区 】
发信人: DaShagen (Unbearable lightness), 信区: Biology
标 题: how to add a biotin to a residue in silico?
发信站: BBS 未名空间站 (Tue Jan 26 18:45:49 2010, 美东)
my friend wants to attach a biotin molecule to a lysine of protein and then
do some energy minimization.
I managed to add the molecule in pymol, but probably it is not in its favora
ble conformation. Anyone can suggest a software to do it?
thanks |
|
w******g
发帖数: 438 | 22 对于hbr,
1. what is the # valence e's in molecule?
2. for bond, polar or non-polar?
3. for molecule, polar of non-polar?
十分感谢 |
|
c****6
发帖数: 2 | 23 A. Hao Xu @ Georgia State University
http://chemistry.gsu.edu/H_Xu.php
Welcome! We are a group of scientists who are interested in novel chemical
reactivity and selectivity, especially in catalytic processes. We are
engaged in two dynamic areas of chemical synthesis: complex-molecule
synthesis and functional synthesis at the chemistry–biology interface.
Complex-molecule synthesis has had tremendous impact on the development of
chemistry, biology and medicine. However, it is a misconception that |
|
t******t
发帖数: 3045 | 24 broad NMR signals of macro molecules (polymers, proteins)are caused by very
fast relaxation, i.e. short t1. t1 of protons in most small molecules are a
few seconds. 13C especially carbonyl 13C that has no protons attached to
have much longer t1, that is why 13C NMR is not as quantitative as 1H NMR.
Unless you want to have very accurate results (errors < 3%), there is no
need to set the relaxation delay to ~5x t1 instead of 1x or 2x t1 since
your experiment run time will be much longer. |
|
s****2
发帖数: 4569 | 25 "Fmoc或者Boc牌的超薄型" not good for big biomolecules, such as protein.
may be convert this "含有氨基的物质"(if small molecule) to COOH, further to
COOSu(or COOSu-SO3Na). Then react with 既含有氨基又含有羧基的物质(large
molecule). |
|
q*****e
发帖数: 433 | 26 给你把那本书的目录贴过来吧
多半你所谓的大牛都在里面了
PART I: INTRODUCTION
Chemistry and Biology -- Historial and Philosophical Aspects (Gerhard
Quinkert, Frankfurt University)
PART II: USING SMALL MOLECULES TO EXPLORE BIOLOGY
Using Small Molecules to Unravel Biological Mechanisms (Tarun Kapoor,
Rockefeller University)
Using Natural Products to Unravel Cell Biology (Craig Crews, Yale
University)
Engineering Control Over Protein Function Using Chemistry (Kevan Shokat,
UC San Francisco)
Controlling Protein Function by Cage |
|
d****n
发帖数: 397 | 27 不知道你问的问题是指什么。
A(molecule)=>B(radical)+C(radical) 这个photodissociation过程需要的光波波长？
还是这个自由基能吸收的光波波长？
有可能你说的自由基B,是这样产生的E(radical)+F(molecule)=>B(radical)。所以，没
有上下文，“算出产生这个自由基需要的光波波长”，不知道怎么算。
cis. |
|
p****u
发帖数: 239 | 28 Reactions - Shuli You
http://blogs.nature.com/thescepticalchymist/2011/06/reactions_s
Shuli You is a Professor of Organic Chemistry in the State Key Laboratory of
Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese
Academy of Sciences, and works on methodology development, total synthesis,
and medicinal chemistry.
1. What made you want to be a chemist?
I was good at chemistry in high school and then chose chemistry as major in
university. Now I really enjoy being a chemist... 阅读全帖 |
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c******n
发帖数: 16403 | 29 Not all molecules can be scaled-up as some of his molecules. 不能拿特例广而
化之。 |
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d******s
发帖数: 674 | 30 I know you can achieve good peak shapes for small molecules on bare silica,
e.g. nicotine. But won't be appropriate using nanoflow, there is nothing
wrong with nanoflow for small molecules just the throughput will be too low. |
|
n*********e
发帖数: 665 | 31 想用dye标记一下polyacrylate高分子，能想到的最简单的办法可能是用free radical
polymerization直接把dye molecule反应到主链中。因为对这个领域不熟悉，找了很久
也没找到可以直接买到的带双键的dye molecule,哪位如果买过这种分子，能不能告诉
我一下，多谢！ |
|
j********e
发帖数: 92 | 32 问题在attached的图片里
已经试了几个sonogashira反应和Suzuki反应， 大部分时间反应混合物是原料+一些乱
七八糟的东西， 个人感觉是位阻太大引起的问题。 希望大牛们提供其他高见怎么做到
target molecule。 我自己已经想过能否用malonate 去取代那个Cl， 然后从那里
extend the chain， 但是即使work了， 步骤好长。。。。
正好碰到节日，提供好建议的同学奖1到10个包子吧， 如果我最后用了某个同学的建议
做出了target molecule， 我再奖100个包子（不好意思， 我穿了马甲上来， 因为觉
得连sonogashira反应都做不出了， 太丢人。 我另外马甲有足够包子可以发）
另外我这个项目如果做成了， 没准我们能“骗"到些VC的钱， 到时招有机化学的人我
一定优先推荐帮我的同学。 |
|
L****r
发帖数: 333 | 33 嘎tech化学 got Younan Xia, in 2011 he publsihed 11 Angewandte Chemie
International Edition.
(1) Silver nanocrystals with concave surfaces and their optical and surface-
enhanced Raman scattering properties
Xia, X.; Zeng, J.; McDearmon, B.; Zheng, Y.; Li, Q. and Xia, Y. Angewandte
Chemie International Edition 2011, 50, 12542-12546 (VIP article, highlighted
on the inside cover).
(2) Shape-controlled synthesis of copper nanocrystals in an aqueous solution
with glucose as a reducing agent and hexadecyl... 阅读全帖 |
|
K*********e
发帖数: 183 | 34 打了好一会儿, 全部没了. 改用英文把. 打中文我不行, 太话时间了.
1. The top -OH lost with the neighboring -H, it forms the conjugate, that is
very stable. But what I meant is when it lost H on that OH, it will not
form conjugate. Maybe I misinterpreted it.
2. Thank you for telling me the 内酯 can lose CO directly, I forgot that.
But when it lose CO2, the ring opened, no ring is there anymore, right?
3. I dealt with a similar molecule which is more acidic than this one, it is
OK in Positive mode. So I thought this molecule sho... 阅读全帖 |
|
K*********e
发帖数: 183 | 35 打了好一会儿, 全部没了. 改用英文把. 打中文我不行, 太话时间了.
1. The top -OH lost with the neighboring -H, it forms the conjugate, that is
very stable. But what I meant is when it lost H on that OH, it will not
form conjugate. Maybe I misinterpreted it.
2. Thank you for telling me the 内酯 can lose CO directly, I forgot that.
But when it lose CO2, the ring opened, no ring is there anymore, right?
3. I dealt with a similar molecule which is more acidic than this one, it is
OK in Positive mode. So I thought this molecule sho... 阅读全帖 |
|
p**********g
发帖数: 378 | 36 老大，你给的 information 太少了啊想帮也帮不了。
先回答几个问题：
Small molecule or large molecule?
Peptide? Ionizable? pH?
sample stability? Temperature?
Column?
Mobile phase? Buffer?
Sample concentration? Diluent?
UV? Wavelength? |
|
w**z
发帖数: 123 | 37 condensation usually requires mingling of two parts together,in addition to
the removal of a small molecule. in this case no of the other molecule (H2)
is integrated to the polymer structure.
However, I would probably call this "condensation" on a more general basis
because it just adds nothing to the polymer structure while extracting HBr. |
|
e***m
发帖数: 725 | 38 有兴趣可以把简历送给我，c*****[email protected]，背景合适我可以帮忙推荐。
公司支持H1B,满一年后支持办绿卡。
这个职位要招fresh PhD或者最多一两年经验。
各位好运。
Title: Scientist I, Oncology Drug Discovery
Responsibilities:
· Design and synthesize small molecule anticancer agents for
discovery programs
· Understand structure-activity-relationship (SAR) using parameters
specific to the project.
· Characterize and analyze the synthesized molecules using standard
analytical methods such as NMR, MS etc.
· Systematic recording of exper... 阅读全帖 |
|
r****o
发帖数: 104 | 39 One postdoctoral position supported by DOE is available immediately. The
successful candidate will conduct research to study the flow behavior of
different fluids and gases in nano-scale porous media (nano-chips) for our
three year DOE funded project. The postdoctoral fellow will design and carry
out experiments, develop mathematical models to understand the fluid flow
behavior in nano-pore-sized porous media. In addition, the successful
candidate will also oversee and guide the research of mult... 阅读全帖 |
|
U**R
发帖数: 34 | 40 Molecular Simulation
Translator disclaimer
Effects of ions on winter flounder antifreeze protein and water molecules
near an ice/water interface
Effects of ions on winter flounder antifreeze protein and water molecules
near an ice/water interface
Preview
Access options
DOI:10.1080/08927022.2011.600759
Kohei Hayakaria & Yoshimichi Hagiwaraa*
pages 26-37
http://www.tandfonline.com/doi/abs/10.1080/08927022.2011.600759 |
|
s*******h
发帖数: 51 | 41 The Asymmetric Catalysis Laboratory at the University of Nevada, Las Vegas
seeks dedicated graduate students interested in design and synthesis of
novel organocatalysts and asymmetric catalysis for the development of new
methodology to apply for the synthesis of bioactive complex molecules.
Job Title: Graduate Student Researcher in Synthetic Organic Chemistry
Institution: University of Nevada, Las Vegas, NV, USA
Department: Chemistry
Department Website: http://www.unlv.edu/chemistry
Kang Group W... 阅读全帖 |
|
B*****n
发帖数: 654 | 42 【 以下文字转载自 Texas 讨论区 】
发信人: Boolean (Soso), 信区: Texas
标 题: 能求个 工作推荐不? polymer chemistry 方向的
发信站: BBS 未名空间站 (Wed Oct 8 18:56:16 2014, 美东)
人在TAMU, 找工作中, 有人能帮帮忙么?
10+ years polymer research scientist/engineer with strong experience in
advanced polymer material synthesis and characterization. Expertise in
polymer coating, extrusion, casting films Rheology analysis of polymeric
systems, polymer additives R&D experience, polymer composites preparation
and nano-material synthesis & characterization. A... 阅读全帖 |
|
H*****9
发帖数: 11 | 43 I now discuss some of the Chinese Classical literature and prep the patient
mentally:
The Huang Di Nei Jing states that the organs produce Qi and that the Qi of
the
different organs have differing functions. However, in healthy people the Qi
of
each organ feeds and balances the receiving organ. This Qi must then travel
from
the Organs to nourish the ends of the fingers, nose, toes, and brain. So, we
have this simplified idea of Qi from the Huang Di Nei Jing. But the magic
questions are, “What is... 阅读全帖 |
|
W******r
发帖数: 789 | 44 来自主题: ChineseMed版 - 西医的本质 I am not an engineer.If the system is simple enough to be described by a
definite mathematical model, then I believe you can do system level
engineering and make things work. However, the human body is not something
you can engineer in the system level, for its complexity will never be fully
understood. Besides, the current conventional medical practice is far from
being at the system level. You see a tumor, you cut it off. You see high
temperature, you use chemicals to block the signals that re... 阅读全帖 |
|
m*******e
发帖数: 119 | 45 EE is a multi-discipline area. Chemistry, especially organic
chemistry, now play more and more important role in EE,
especially in novel electronic and optical devices.
To name a few examples:
1. molecular electronics. Current scaling rule for Si based
electronics will reach its physical limitation in the next
15 to 20 years. Now lots of hot research involves using
single organic molecule as electronic devices. Single
molecule diode is not a news today. These devices can be
super tiny which can |
|
q******s
发帖数: 7 | 46 郑上游教授目前在新加坡南洋理工大学任教，就职于物理及应用物理系。从2012年8月
开始，他的课题组有两个博士生名额开始招收，希望有志于Soft Condensed Matter
Physics, Single Molecule Physics, Biophysics等方面研究的博士生申请他的科研组
。博士生会有全额的奖学金资助。有相关研究经历的博士后，也欢迎申请他的课题组。
此课题组有一个特别的交流计划，博班期间，博士生将去宾夕法尼亚大学或哈佛大学与
郑教授前老板进行3〜6月的研究。
南洋理工大学这些年在飞速进步, 特别是工程及物理学院, 科研已具有非常高的水平。
学校科研投入也很大。感兴趣的同学可以参看学校的网页: www.ntu.edu.sg (School
of Physical and Mathematical Sciences).
请感兴趣的同学直接跟郑教授联系，把简历发到他的邮箱：
s***[email protected]
Phone: (65)-6592-3148
Prof. Shang-You Tee (School of Physical and Mathema... 阅读全帖 |
|
s****1
发帖数: 425 | 47 有些书全新，其它书里面也没有笔迹。有感兴趣的同学发信给我，可以提供详情。廉价
处理
18,Microwave engineering, David M. Pozar, 3th ed.
19，Principles of the theory of solids, J.M.Ziman
20,Superconductive devices and circuits, Theodore Van Duzer and Charles W.
Turner
21, Design of Analog CMOS integrated circuits, Behzad Razavi
1,Atom Optics, Pierre Meystre
2,Physics of atoms and molecules, B.H. Bransden and C.J. Joachain
3,Quantum optics, Marlan O.Scully and M. Suhail Zubairy
4,Nonlinear optics, Robert W. Boyd
5,Elements of quantum optics,... 阅读全帖 |
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J****y
发帖数: 19 | 48 来自主题: Macromolecules版 - 请帮助 那位大虾能告诉我我的换算对吗？
number molecular weight of this polymer is 495000 g/mole.
The number of atoms in a mer is 15 and the weight of mer =100 g/mile.
The density of the polymer is about 1 g/cm3.
So I am wondering if I can do the following calculation for 1 cm3 polymer
to know how many atoms I have:
Mass=1g=1/495000 mole
#of molecule =1/495000 *avogadro's numer =B
( 这儿， 不知道可不可以这样对POLYMER计算？？？HELP)
# of atoms=B*(495000/100=# of mer/molecule)*15 (# of atoms per mer)
这个计 |
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w********h
发帖数: 12367 | 49 来自主题: Macromolecules版 - 牛人们
Zhuang XW, Kim H, Pereira MJB, et al.
Correlating structural dynamics and function in single ribozyme molecules
SCIENCE 296: (5572) 1473-1476 MAY 24 2002
Fernandez JM, Chu S, Oberhauser AF
RNA structure - Pulling on hair(pins)
SCIENCE 292: (5517) 653-654 APR 27 2001
Zhuang XW, Bartley LE, Babcock HP, et al.
A single-molecule study of RNA catalysis and folding
SCIENCE 288: (5473) 2048-+ JUN 16 2000
Smith DE, Babcock HP, Chu S
Single-polymer dynamics in steady shear flow
SCIENCE 283: (5408) 1724- |
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c*********e
发帖数: 119 | 50 from http://www.psrc.usm.edu/macrog/index.htm
So you want to know just how and why these polymers, these macromolecules, act
differently from small molecules. So we'll tell you. That's just the kind of
nice people we are. There are, for those of you who didn't bother to read the
title, three ways in which polymers will act differently from small molecules.
And the reasons are a little bit more complicated than just "because they're
bigger". The three are usually named:
Chain entanglement
Summati |
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