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l******t
发帖数: 505 | 1 最好是proteomics或者摩tablites啊，正儿八经的传统的，别的什么纳米技术纳米材料
用在质谱上的就算了啊。 | y*****s
发帖数: 1047 | 2 搞omics都不是正儿八经传统的
多得很，都在生物的系，医院 | b*******g
发帖数: 1309 | 3 Richard Smith
John Yates
Nail Kellher
都是做分析出身吧，呵呵
BTW，我们组一口气刚招了两个，早点就好了。。
【在 y*****s 的大作中提到】
: 搞omics都不是正儿八经传统的
: 多得很，都在生物的系，医院
| y*****s
发帖数: 1047 | 4 我只是对lz“正儿八经传统”而言
质谱只是个工具
正儿八经传统的是用质谱解决化学的问题
omics是解决生物问题，当然就不是正儿八经传统的了
【在 b*******g 的大作中提到】
: Richard Smith
: John Yates
: Nail Kellher
: 都是做分析出身吧，呵呵
: BTW，我们组一口气刚招了两个，早点就好了。。
| b*******g
发帖数: 1309 | 5 现在的质谱大都是基于生物问题的，否则咋叫bioMS
国内直接就叫生物质谱。。哈哈
【在 y*****s 的大作中提到】
: 我只是对lz“正儿八经传统”而言
: 质谱只是个工具
: 正儿八经传统的是用质谱解决化学的问题
: omics是解决生物问题，当然就不是正儿八经传统的了
| l******t
发帖数: 505 | 6 嗯，俺说的正而八经就是指把小分子，omics什么的全算在内了，研究的课题也正统一
点，不说完全有用，但是不要像有些课题似的整个纳米材料跟质谱毫无用处。俺现在很
反感有些课题打着新奇的幌子到处招摇撞骗，实际上就是见光死，除了哄哄NIH NSF啥
用没有。 | l******t
发帖数: 505 | | y*****s
发帖数: 1047 | 8 广告都多得很
Posted/Revised: 5/2/2012
Company/Institute: Pfizer Inc
Department:
Position: 2 Year Postdoctoral Fellow – Protein Quantitation in Tissues
by Mass Spectr
Job Location: Andover, MA United States
Description: 2 year Postdoctoral Fellow – Protein Quantitation in
Tissues by Mass Spectrometry and Immunoanalytical Techniques A Postdoctoral
Fellowship is available in Pfizer’s Pharmacokinetics Dynamics and
Metabolism New Biological Entities (PDM-NBE) in Andover, MA. The PDM unit
provides leading capabilities in support of Pfizer’s biotherapeutics
portfolio. A key contribution of the unit is to utilize state-of-the-art
bioanalytical technology to provide knowledge for preclinical systems-based
PK/PD modeling, enabling translation to humans and ultimately improving the
quality of clinical candidates and reducing late-stage attrition. Success in
translation depends on the reliability of the models and the accuracy of
the biological systems parameters (‘biomeasures’) that define them. To
advance our technical capabilities for biomeasure determinations in tissue (
oftentimes the site-of –action) we are seeking an outstanding post-doctoral
fellow to systematically explore precise and accurate quantitation methods
of soluble and membrane bound proteins in tissues. This will include
optimization of tissue homogenization, protein extraction techniques and the
establishment of novel, universal normalization tools such as tissue stable
isotope labeling and SILAC to enable the use of innovative protein LC-MS/MS
and immunoassay approaches. The expectation is that the results from these
studies will be published in top tier journals setting the foundation for a
career in academia or industry. Qualifications & technical competencies &#
8226; Doctoral degree in Analytical Sciences, Biochemistry, Chemistry or
closely related fields with 0-2 years of postdoctoral experience. •
Experience in quantitative protein mass spectrometry or targeted proteomics
is essential. • Established track record applying innovative
methods to drive project success. • Strong analytical, protein and
enzyme biochemistry background, experience with membrane biochemistry, good
understanding of concepts of immunology based analytical methods •
Able to work as part of a team • Excellent communication skills,
both written and oral. Responsibilities: • Development and
characterization of quantitative bioanalytical assays for tissue biomeasure
based on LC-MS/MS and immunoanalytical tools (includes nanoflow
chromatography; high resolution and triple quadrupole mass spectrometry;
protein biochemistry including digestions, modifications and separations;
antibody enrichment; immunoassays ) • Handling of biological samples,
specifically tissues.
Degree: PhD;
Field of Study: Biochemistry; Chemistry; Analytical Chemistry;
Industry: Pharmaceutical;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: Bio-analysis; Electrospray ionization; HPLC; LC-MS
; Pharmaceuticals; Proteomics; Quantitation;
Contact: DAWN R. DUFIELD
Address: 1 Burtt Rd
Andover, MA
Email: d************[email protected] Phone:
Conference Contact: Dawn Dufield Cell or Hotel Phone: Vancouver
Marriott Pinnacle Downtown
Conference Location and/or Email: d************[email protected]
Posted/Revised: 5/1/2012
Company/Institute: Pacific Northwest National Lab
Department: Biological Separations and Mass Spectrometry
Position: Postdoctoral Position in Quantitative Proteomics
Job Location: Richland , Washinton United States
Description: This postdoctoral position requires a highly motivated,
adaptable, and capable individual with a PhD degree preferably in
biochemistry or analytical chemistry. The research involves a range of
proteomics technologies and methodologies to solve exciting biological
challenges, including e.g., targeted proteomics to quantify proteins for
pathway analysis or verification of protein candidates for diagnosis,
prognosis, and therapeutics from cells, tissues, and biofluids. The ideal
candidate would preferably have hands-on experience in mass spectrometry,
proteomics, LC separations, data analysis and possibly biology domain
specific experience (such as cancer, diabetes, pathogen biology, or
bioenergy research). Research may include include methods development,
sample preparation and separation methods for enhancing reproducibility, and
specific protein candidate verification in different sample types. The
successful candidate will be expected to work effectively with an
interdisciplinary team of researchers, be self motivated, and have excellent
communication skills. The successful candidate is expected to assist and
lead the preparation and presentation of papers, posters, reports, etc. This
is a full-time limited term employment position. The duration of this
appointment is two years, with the option of extending the appointment up to
three years, depending on project funding and individual performance.
Candidates must have received a PhD within the past five years from an
accredited college or university. All staff at the Pacific Northwest
National Laboratory must be able to demonstrate the legal right to work in
the United States. Strong organization and communication skills are needed
to work efficiently in a team environment. Background in Biochemistry,
Chemistry, Biology, Bioinformatics, or a closely related field is required.
Degree: PhD;
Field of Study: Biochemistry; Chemistry; Analytical Chemistry;
Industry:
Job Roles: Res. & Dev. Scientist;
Area(s) of Expertise: LC-MS; Proteomics; Quantitation;
Contact: Dave Camp
Address:
, WA
Email: d*******[email protected] Phone:
Conference Contact: Cell or Hotel Phone:
Conference Location and/or Email:
Posted/Revised: 4/28/2012
Company/Institute: Stanford
Department: Chemical and Systems Biology
Position: Postdoctoral Position in Quantitative Proteomics and Systems
Biology
Job Location: Stanford, CA United States
Description: Job Description: We are seeking a dynamic, enthusiastic
postdoctoral scholar to join our lab in the Dept. of Chemical and Systems
Biology in the Stanford University School of Medicine. The Teruel laboratory
is focused on understanding the Systems Biology of Cell Differentiation and
Cell Signaling. We are particular interested in adipogenesis and PI3K-
insulin signaling. To make new insight into the molecular mechanisms by
which these processes control insulin resistance, type II diabetes, and
other metabolic diseases, our lab develops and applies innovative targeted
mass-spectrometry, as well as live-cell fluorescence microscopy, molecular
biology, and modeling approaches. Our lab possesses its own state-of-the-art
instrumentation including a highly sensitive Thermo-Fisher TSQ Vantage
triple-quad mass spectrometer with Proxeon nanoHPLC. Requirements:
Candidates must have received a recent Ph.D. degree and have one or more
publications in peer-reviewed journals. Experience in at least one of the
following areas is required: mass spectrometry, proteomics, biochemistry, or
analytical chemistry. This position requires strong verbal and written
communication skills and the ability to interact with others with diverse
areas of expertise. Candidates who possess a strong motivation to pursue
academic research are encouraged to apply. Interested candidates should e-
mail their CVs, brief statement of interest, contact information, and three
references to the email address below: Contact: Mary Teruel, Ph.D. Email:
m*****[email protected] Phone: (650) 721-2045
Degree: PhD;
Field of Study: Biochemistry; Analytical Chemistry; Medicine;
Industry: Academic/Research Institution;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: Bioinformatics; Electrospray ionization; HPLC; LC-
MS; Peptide sequencing; Proteomics; Quantitation;
Contact: Mary Teruel
Address: 269 Campus Drive, CCSR 3155B
Stanford, CA
Email: m*****[email protected] Phone: 650-721-2045
Conference Contact: Mary N. Teruel Cell or Hotel Phone:
Conference Location and/or Email: m*****[email protected]
Posted/Revised: 4/27/2012
Company/Institute: Stanford University
Department: Canary Center for Cancer Early Detection
Position: Postdoctoral Position with Experience in Mass Spectrometry and
Proteomics
Job Location: Stanford , CA United States
Description: Environment: The Canary Center at Stanford is a newly
opened world-class facility dedicated to cancer early detection research
programs. The mission of the center is to foster research leading to the
development of blood tests and molecular imaging approaches to detect and
localize early cancers. The Multi-scale Diagnostics Laboratory, within the
Canary Center, hypothesizes that accurate methods for simulating cancer’s
multi-scale properties may lead to dramatic advances in the discovery and
application of approaches to personalize cancer care. Job Description: We
are looking for a highly-qualified, and creative postdoctoral fellow with an
active interest in mass spectrometry and quantitative proteomics. The ideal
candidate will be an energetic scientist with excellent written and verbal
communication skills. The ideal candidate will have an analytical chemistry,
biochemistry, or protein chemistry background. The successful applicant
will work in a laboratory focused on the development of quantitative
proteomics methods towards interrogating whole-proteome protein dynamics
specifically, their translation and degradation rates. Requirements:
Necessary skills include a recent PhD or current postdoctoral position in
analytical chemistry, quantitative proteomics, systems biology or chemical
or biological sciences with two or more publications in peer-reviewed
journals. The qualified candidate will be primarily responsible for mass
spectrometry-based proteomics studies and will have the opportunity to
design protein dynamics studies incorporating a range of samples from model
samples (e.g. sets of exogenously purified proteins) as well as samples
derived from in vitro (mammalian cell culture) studies, or samples derived
from in vivo (murine) studies. A combination of quantitative proteomics
techniques will likely be employed. The ideal candidate will be comfortable
with trouble-shooting/optimizing LCMS workflows and generating large-scale,
quantitative datasets. Familiarity with cancer cell biology, bioinformatics,
systems biology or high throughput biologic analysis is preferred, but not
essential. The successful new hire will be highly self-motivated and
creative. It is imperative that the candidate be comfortable interacting
with scientists whose backgrounds are extremely diverse to work effectively
in our multi-disciplinary team. Key factors in the success of this job
include: high levels of attentiveness to detail, ability to collaborate
closely with others and willingness to learn. Salary will be based on
University guidelines for postdoctoral fellows, and will be commensurate
with experience. Stanford University is an Equal Opportunity/Affirmative
Action Employer. Interested applicants please submit CV, brief statement of
interest and career goals, contact information and three references to the e
-mail address below:
Degree: PhD;
Field of Study:
Industry: Academic/Research Institution;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: HPLC; LC-MS; Proteomics;
Contact: PARAG MALLICK
Address: 1501 S California Avenue
Palo Alto, CA
Email: p****[email protected] Phone:
Conference Contact: Parag Mallick Cell or Hotel Phone:
Conference Location and/or Email: j**[email protected]
Posted/Revised: 4/26/2012
Company/Institute: Henry Jackson Foundation
Department: Obstetrics and Gynecology
Position: Postdoctoral Fellow
Job Location: Fairfax, VA, Virginia United States
Description: A postdoctoral research fellowship is immediately available
in the Department of Obstetrics and Gynecology at Inova Fairfax Hospital (
IFH) in Fairfax Virginia. This position will dual report to Larry Maxwell,
MD, Chairman of OB/Gyn at IFH and Thomas Conrads, PhD, Chief Scientific
Officer of the Women’s Health Integrated Research Center (WHIRC) at Inova
Health System. The successful candidate will contribute to research using
advanced techniques in mass spectrometry and quantitative proteomics for
investigations in gynecologic cancer and other women’s health-related
pathologies, including pre-term birth and placental accreta. The projects
are specifically aimed at development and application high resolution mass
spectrometric techniques for differential identification and label-free
quantification of protein biomarkers from tissue biopsies, proximal fluids
and serum. The projects will involve technical developments in mass
spectrometry toward improved analytical precision and throughput for assay
of these clinical samples using mass spectrometry. The WHIRC at Inova
infrastructure comprises state-of-the-art instrumentation for next-
generation sequencing, mass-spectrometry-based proteomics (2 Orbitrap Velos
and 2 Q-Exactives) and computational biology that enables cutting-edge
molecular profiling and translational research in women’s health. To
qualify, candidates must have a Ph.D. in the biological or physical sciences
. A strong record of research accomplishments and publications, the ability
to work in a team environment, excellent oral and written communications
skills in English, presentations of scientific results at national meetings
and their publication in peer-reviewed journals are required. Required
skills include demonstrated experience in conducting nanoscale liquid
chromatography-mass spectrometry, laser capture microdissection, proteomic
sample preparation and post-acquisition proteomic bioinformatics analysis.
Previous work in molecular biology, cell biology, or biochemistry is highly
desired. Interested candidates should email a cover letter and CV to conrads
@whirc.org.
Degree: PhD;
Field of Study: Biochemistry; Chemistry; Analytical Chemistry;
Industry: Academic/Research Institution;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: LC-MS; Proteomics;
Contact: Thomas Conrads
Address: 3289 Woodburn Rd
375
,
Email: c*****[email protected] Phone:
Conference Contact: Cell or Hotel Phone:
Conference Location and/or Email:
Posted/Revised: 4/25/2012
Company/Institute: Pacific NW Nat'l Lab
Department: Environmental Molecular Sciences Laboratory
Position: Postdoctoral research associate in the field of MS
instrumentation developm
Job Location: Richland, Washington United States
Description: The Mass Spectrometry (MS) Capability at the Environmental
Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory
is seeking a postdoctoral research associate in the field of MS
instrumentation development. The successful candidate is expected to
participate in design and construction of state-of-the-art MS capabilities
including FTICR MS, advanced MS based imaging, TOF, and ion mobility
platforms and to apply these methods to biologically relevant problems. We
seek highly qualified candidates with experience in one or more of the
following areas: FTICR MS, data acquisition systems, MS experiment control
and automation, data processing and analysis, vacuum system design and
control, MALDI, SIMS, ESI and TOF MS. This would be a fantastic opportunity
for self-motivated individuals who want to continue learning and developing
leading edge technologies and applications (e.g. top-down MS). The
successful candidate must be highly motivated and interested in expanding
his/her background while working in an interdisciplinary team-based
environment.
Degree: PhD;
Field of Study: Biochemistry; Chemistry; Analytical Chemistry;
Industry: Government;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: Bioinformatics; Bio-analysis; Electrospray
ionization; Elemental Analysis; Fundamentals; GC-MS; Ion Chemistry; HPLC; LC
-MS; Lipids; Natural Products; Peptide sequencing; Proteomics; Quantitation;
Carbohydrates-Glycobiology; Electrical Engineering; Hardware Maintenance;
Electronics; Hydrocarbon Analysis;
Contact: LJILJANA PASA-TOLIC
Address: PO Box 999, MSIN: K8-98
902 Battelle Blvd.
Richland, WA
Email: l****************[email protected] Phone: 509 371-6585
Conference Contact: Cell or Hotel Phone:
Conference Location and/or Email:
Posted/Revised: 4/19/2012
Company/Institute: Northeastern University
Department: Chemistry and Chemical Biology
Position: Postdoctoral Fellow
Job Location: Boston, MA United States
Description: An NIH-funded postdoctoral position is now available with
Prof. John R. Engen in the Department of Chemistry and Chemical Biology at
Northeastern University in Boston. The project will involve studies of
protein conformation and dynamics with hydrogen exchange mass spectrometry.
Our laboratory has many interactions with collaborators in Boston on
exciting projects of medical relevance. Visit the group website at http://www.hxms.neu.edu for more information and a list of recent publications. Applicant must be highly motivated with a successful track record, including publications. A PhD in molecular biology, biochemistry, chemistry or related field and a strong background in protein analysis are required. Skills in protein expression, hydrogen exchange and protein analysis by ESIMS preferred. To apply, send a complete CV and the names of 3 references to Prof. John R. Engen, j*****[email protected]. Informal inquiries are also welcome at the same email. Interviews will be conducted at the ASMS meeting in Vancouver.
Degree: PhD;
Field of Study: Biochemistry; Chemistry; Analytical Chemistry;
Industry: Academic/Research Institution;
Job Roles: Post-Doctoral Fellowship;
Area(s) of Expertise: Bio-analysis; Electrospray ionization; HPLC; LC-MS
; Proteomics;
Contact: JOHN R. ENGEN
Address: 360 Huntington Avenue
Chemistry & Chemical Biology
Boston, MA
Email: j*****[email protected] Phone: 617-373-6046
Conference Contact: Cell or Hotel Phone:
Conference Location and/or Email: | k****o
发帖数: 728 | 9 正儿八经的质谱也是用化学解决质朴的问题。比如ETD。
【在 y*****s 的大作中提到】
: 我只是对lz“正儿八经传统”而言
: 质谱只是个工具
: 正儿八经传统的是用质谱解决化学的问题
: omics是解决生物问题，当然就不是正儿八经传统的了
| l******t
发帖数: 505 | | | | l******t
发帖数: 505 | 11 其实我挺想做proteomics里面bioinformatics和质谱相结合的那部分，本人颇有些质谱
硬件的经验，喜欢装仪器改仪器，也做了一段时间的proteomics，但是目前没啥关于
proteomics文章，编程方面有点基础和兴趣但从没正规训练过。不知这种背景找个类似
的博后职位难不难则个？ | y*****s
发帖数: 1047 | 12 from ASMS
【在 l******t 的大作中提到】
: 谢谢yaofans信息，不知你从哪里找到的？
| h*****t
发帖数: 1226 | 13 千万不要搞个“四不像”。
现在正经的bioinfor的博士和硕士都不好找工作。 喜欢硬件的就去仪器公司。
【在 l******t 的大作中提到】
: 其实我挺想做proteomics里面bioinformatics和质谱相结合的那部分，本人颇有些质谱
: 硬件的经验，喜欢装仪器改仪器，也做了一段时间的proteomics，但是目前没啥关于
: proteomics文章，编程方面有点基础和兴趣但从没正规训练过。不知这种背景找个类似
: 的博后职位难不难则个？
| l******t
发帖数: 505 | 14 是吗，我怎么感觉既懂硬件又懂formatics的人都是人才？虽然俺喜欢硬件，仪器公司
都不瞟俺一眼，哎,有经验没相关文章。 | y*****s
发帖数: 1047 | 15 我怎么觉得仪器公司招的不是到处修仪器就是到处推销的
一天到晚出差
【在 h*****t 的大作中提到】
: 千万不要搞个“四不像”。
: 现在正经的bioinfor的博士和硕士都不好找工作。 喜欢硬件的就去仪器公司。
| l******t
发帖数: 505 | 16 真正做质谱的牛牛都是物理或ee的吧，化学的都是application而已，顶多研究下怎么
组装 | b*********2
发帖数: 190 | 17 omics的方向学校，研究所和医院比较多，工业界的需求有限。看你以后想干啥了。 | l******t
发帖数: 505 | 18 俺想进工业界，请提点一下工业界应该干些啥或者找个啥方向的组？
【在 b*********2 的大作中提到】
: omics的方向学校，研究所和医院比较多，工业界的需求有限。看你以后想干啥了。
| y*****s
发帖数: 1047 | 19 工业界做的 pharmacology, formulation
学校都看不上
omics啥的 NIH舍得烧 公司舍不得烧 |
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