W*******n
发帖数: 4140 | 1 我的2011年版找工简历
王利民
2014年8月16日
（现注：当时，未列出2010年在Fox Chase Cancer Center的经历；没列出2005年在
Memorial Sloan-Kettering Cancer Center的经历；没列出2006年在陕西师范大学、
2009年在江南大学任教的经历。）
Career Summary:
PhD degree on Chemistry and post-doctoral research on protein
structure in the USA; Teaching (assistance) experience in the USA and
China; Customer service experience in the USA.
Work/ Research:
Jan 2006 - : various work in the USA, China, and home.
Sept. 2003- June 2005: New York State Department of Health
Post-doctorate
Research projects: Crystal structure studies on superantigen/receptors
complexes (MAM and HERV superantigens); chimeric rubredoxins; and non-
structural proteins of flaviviruses.
Major findings: Crystal structure of a ternary immune complex of
murine scTCR (T7, modified from CD8+ T cell clone), superantigen MAM,
and human pMHC II (HA-DR1), which shows that the superantigen bridges
scTCR and pMHCII, and the superantigen interacts with TCR both and
α
chains.
Hands-on skills: molecular cloning; E. coli culture; protein
purification; crystallization; data collection, structure
determination and refinement.
Education:
Aug. 1999- Aug. 2003: Rensselaer Polytechnic Institute
Ph.D. in Chemistry
Research project: structural studies on Serum Amyloid A (SAA) protein
and its amyloid fibril formation in vitro. SAA is a major acute phase
reactant, and bound to high-density lipoprotein.
Major findings: Protein SAA has a marginal structural stability, so it
is very labile to significant structural changes on the 2°, 3°, and 4°
structural levels due to its primary structural or environmental
changes. During its amyloid fibrillization, SAA can misfold into
oligomeric intermediate of specific stoichiometry, e.g., apparent
octomer for SAA2.2..
Courses GPA: 3.56/4 (30 major credits)
Hands-on skills: E. coli culture; protein purification; protein
structural analysis by dynamic light scattering, UV spectroscopy,
circular dichroism, fluorescence spectroscopy, chemical cross-linking,
partial proteolysis, and computational prediction.
Sept. 1991- July1999: Peking University, Life Science College
Major: biochemistry and molecular biology
Master’s in Science (July 1999)
Bachelor’s in Science (July 1996)
Note: The first academic year was for mandatory military training, due
to Peking University’s involvement in the 1989 political movement.
Other Experiences:
manuscript writing; Western blot; transmission electron microscopy;
mass spectrometry; surface plasmon resonance; analytical
ultracentrifugation; insect cell culture for membrane protein.
Honor:
Highest score in the 1991' National College Entrance Exam in Hunan
Province, China
Published:
1. Nat. Struct. Mol. Biol. 14: 169-71 (2007).
2. Biochemistry 46: 5562-9 (2007).
3. BMC Struct. Biol. 7: 81 (2007).
4. Prot. Sci. 14: 1811-7 (2005).
5. Amyloid the Journal of Protein Folding Disorders 12: 139-48
(2005).
6. Biochem. Biophys. Res. Commun. 317: 157-61 (2004).
7. Proc. Natl. Acad. Sci. USA 99: 15947-52 (2002).
8. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 17: 51-3 (2000). |
|
