T**********e
发帖数: 29576 | 1 HPV Vaccines May Be Less Effective for Black Women: Study
MONDAY, Oct. 28 (HealthDay News) -- Black women may get less protection than
whites from the vaccines recommended for preventing human papillomavirus (
HPV), which causes cervical cancer, a new study suggests.
The currently available vaccines, Gardasil and Cervarix, don't target the
types of HPV infection found most often in black women, the study authors
said.
Experts have long believed that most cervical cancers are caused by
persistent infection with subtypes of the sexually transmitted virus known
as HPV 16 and HPV 18. These are the strains targeted by Gardasil and
Cervarix. (Gardasil also targets HPV 6 and HPV 11.)
But black women tend to develop cancer of the cervix -- the lower part of
the uterus or womb -- and die from it more often than white women, even when
screening programs are similar, according to background information
included in the study. This led the researchers to wonder if blacks might be
less likely to benefit from vaccination.
"HPV 16 and 18 occur less frequently in African-Americans than in whites,"
said study researcher Cathrine Hoyo, associate professor of obstetrics and
gynecology at the Duke University School of Medicine.
Hoyo's team looked at women who had abnormal results on Pap tests --
screenings to detect precancerous cervical abnormalities.
Of the nearly 600 women with Pap smear abnormalities in the study, about 86
percent had detectable HPV, Hoyo said.
"African-Americans had half the HPV 16 and 18 frequency as whites did," said
Hoyo, who is scheduled to present the findings Monday at a conference of
the American Association for Cancer Research in National Harbor, Md.
The findings, if replicated in larger studies, could call into question the
effectiveness of the current vaccines for all races, she said.
But women should still get an HPV vaccine, said Dr. Robert Morgan, co-
director of the gynecological oncology program at the City of Hope
Comprehensive Cancer Center in Duarte, Calif. "I don't think recommendations
on vaccination would change [based] on this data," said Morgan, who was not
involved in the research.
The American Cancer Society estimates that more than 12,000 new cases of
cervical cancer will be diagnosed this year, and more than 4,000 women will
die of the disease. Blacks are about 20 percent more likely to get cervical
cancer, Hoyo said, and about twice as likely to die from it as white women.
The U.S. Centers for Disease Control and Prevention recommends HPV
vaccination for preteen boys and girls at age 11 or 12, before sexual
activity begins. The vaccines, given in three injections over a six-month
period, cost about $400 or more total.
In developing Gardasil and Cervarix, scientists relied on studies to
pinpoint the strains of HPV most likely to lead to cancer. Studies were done
on all ethnicities, Hoyo said, noting that there may have been insufficient
numbers of black women in the research studies to pick up the differences
in HPV subtypes.
"There has always been some skepticism about whether there are other strains
that are important, other than 16 and 18," she said. This study is not the
first to report the differences, she said.
The findings, however, are not a reason for blacks not to get an HPV vaccine
, Hoyo said. Testing of vaccines that target additional HPV subtypes are
under way, and in time the problem may be solved, she added.
Read more at http://www.philly.com/philly/health/womenshealth/HealthDay681480_20131028_HPV_Vaccines_May_Be_Less_Effective_for_Black_Women__Study.html#csitiIOB4O6dArpB.99 | n******g
发帖数: 17225 | | x*****u
发帖数: 6559 | | T**********e
发帖数: 29576 | 4
黑牛最好不要上，要上也一定带套，HPV比例比白牛高很多。
【在 n******g 的大作中提到】
: 擦!
| T**********e
发帖数: 29576 | 5
呵呵，那是因为国女窄而紧，匹配进化需要。
【在 x*****u 的大作中提到】
: 中国人jj小，是基因宗族歧视？
| n******g
发帖数: 17225 | 6 本来也不喜欢黑妞.我就是觉得病毒怎么也势利眼呢?
有没有可能当初疫苗研发的时候主要志愿者都是白妞，所以样本有偏？
【在 T**********e 的大作中提到】
:
: 呵呵，那是因为国女窄而紧，匹配进化需要。
| n******g
发帖数: 17225 | 7 靠，带套这事儿最好都带吧，白妞也危险。
除非是真的是serious relationship的时候可以考虑bareback
【在 T**********e 的大作中提到】
:
: 呵呵，那是因为国女窄而紧，匹配进化需要。
| T**********e
发帖数: 29576 | 8
是啊，黑女的HPV类型分布不一样，研发时候黑女的样本太少，结果推出疫苗对很多黑
女效果不好。
【在 n******g 的大作中提到】
: 本来也不喜欢黑妞.我就是觉得病毒怎么也势利眼呢?
: 有没有可能当初疫苗研发的时候主要志愿者都是白妞，所以样本有偏？
| T**********e
发帖数: 29576 | 9
是，受良好教育的白牛也不会一开始就同意无套，怀孕和传染的风险都有。谨慎点对双
方都好。
【在 n******g 的大作中提到】
: 靠，带套这事儿最好都带吧，白妞也危险。
: 除非是真的是serious relationship的时候可以考虑bareback
| M*****t
发帖数: 1842 | 10 查个STD又不麻烦。
【在 T**********e 的大作中提到】
:
: 是，受良好教育的白牛也不会一开始就同意无套，怀孕和传染的风险都有。谨慎点对双
: 方都好。
| b****l
发帖数: 23606 | 11 裤子穿的太早了，jj大小这个性征太早退出竞争。
【在 x*****u 的大作中提到】
: 中国人jj小，是基因宗族歧视？
| T**********e
发帖数: 29576 | 12
date几次就要求查std？另外还有怀孕风险。
【在 M*****t 的大作中提到】
: 查个STD又不麻烦。
| T**********e
发帖数: 29576 | 13
看来像罗马男一样用块小布兜着最进化jj，中国宽袍大袖造成性特征退化。
【在 b****l 的大作中提到】
: 裤子穿的太早了，jj大小这个性征太早退出竞争。
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