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a******n
发帖数: 91 | 1 刚刚经历了噩梦般的miscarriage，7周,第一次us没有胎心,然后就自己流掉了，真不知
道生二宝还要经历这种磨难.不知道版上有多少mm和我一样,有没有什么办法可以
prevent? | t*******r
发帖数: 2293 | 2 就是年龄大了， 卵子质量在下降， 和是不是老二没啥联系。 要是人家二十几， 生老
三老四都没有问题。 慢慢试试， 就会有的。 35 会是个分水岭。 35 以后会更难一些
。
Pat pat! 年龄对大家都一样。 | a******n
发帖数: 91 | 3 偶还不到35的说啊
★ 发自iPhone App: ChineseWeb 7.8
【在 t*******r 的大作中提到】
: 就是年龄大了， 卵子质量在下降， 和是不是老二没啥联系。 要是人家二十几， 生老
: 三老四都没有问题。 慢慢试试， 就会有的。 35 会是个分水岭。 35 以后会更难一些
: 。
: Pat pat! 年龄对大家都一样。
| c**t
发帖数: 94 | 4 不见得跟年龄有关 跟保养也很有关係吧 我都38了 挺注重养生的 去年今年都生 都开
玩笑自己像生蛋一样 现在怕死再有第三次accident. | n****8
发帖数: 4141 | 5 认识好几个怀老二都流产了，原先以为既然第一个很顺利，第二个应该也是很容易，没
想到第二胎流产还挺常见的。不知是不是怀老二的时候还要照顾老大，太累，或是两个
之间太近身体还没恢复好？我家老二跟老大中间隔了九岁，倒是很顺利。我妹老大不到
一岁半就又怀上了，就流产了。 | n****8
发帖数: 4141 | 6 July 2003
From European Society for Human Reproduction and Embryology
Women are more likely to suffer recurrent miscarriages if their first child
is a boy
Madrid, Spain: Women who give birth to a boy as their first child are more
likely to suffer subsequent miscarriages than women whose first baby is a
girl, an international conference of fertility experts heard today (Tuesday
1 July).
Dr Ole Christiansen, a consultant registrar at the Rigshospitalet Fertility
Clinic in Copenhagen, Denmark, told the annual conference of the European
Society of Human Reproduction and Embryology, that giving birth to a boy
first was not only a risk factor for subsequent miscarriages, but for women
who suffered unexplained secondary recurrent miscarriages (SRM) it could
mean that they never managed to carry a child to full term again unless
doctors gave them appropriate treatments.
Dr Christiansen said: "Giving birth to a son is known already to be a
prognostically negative factor in many obstetrical complications. Therefore
we wanted to assess the impact of the gender of the first child on the
outcome of subsequent pregnancies among patients with unexplained secondary
recurrent miscarriages.[1]"
He studied 204 SRM patients admitted to clinics between 1986 and 2000, and
obtained information on subsequent pregnancy outcome in 181 patients
admitted before 2000. Among the patients admitted before 2000, only 54.4% of
those who gave birth to a boy in their first pregnancy had given birth to a
second live baby by January 2002, compared with 73% of women whose first
child was a girl.
Amongst a subset of women who did manage to have a second child after a
series of miscarriages, those whose first child was a boy had an average of
3.9 miscarriages before achieving a second birth, while women whose first
child was girl had 3.5 miscarriages before delivery of a second child &#
65533; a small but statistically significant difference. Average birth
weights of the second children tended to be 181g higher where the first-born
was a girl.
Dr Christiansen said: "Our study shows that the majority (54.4%) of those
who gave birth to a boy in their first pregnancy go on to have a second
child. However this percentage is lower than for those who gave birth to a
girl first. Among my patients I have at least 50 who never have a second
child after the first birth of a boy, whereas approximately 20 patients did
not experience another birth after having a girl. So there are patients who
will never get a second child in both groups, but the risk is larger among
women whose first child was a boy."
He believes that the way women's immune systems react to male foetuses is
the explanation for his finding and that therefore it will be possible to
treat successfully women who suffer from SRMs. "These women may have raised
an immunological reaction against tissue types that are expressed on the
surface of the placenta in pregnancies with boys," he said. "The placenta is
created from the foetus and if it is a boy it will carry these male-
specific tissue types. The mother's immune system may be reacting by forming
antibodies, but also the mother's white blood cells may be reacting against
the placenta."
The first pregnancy is able to proceed to full term because the pregnancy is
safely established by the time the mother's immune system starts to react
to the male foetus. However, it is possible that the immune systems remains
activated after delivery and affects subsequent pregnancies, believes Dr
Christiansen.
"This is an epidemiological study, so we cannot be sure that such an
immunological reaction is the explanation for our findings. However, no
genetic disorder following the known rules of inheritance, can explain the
findings. The impact of the gender of the first-born child on successive
pregnancies is suggestive of something that has memory and only two tissues
in the body are thought to have memory: the central nerve system and the
immune system. Together with a PhD student, I have planned a series of
genetic studies and immunological experiments to confirm or reject the
theory of an impact of male specific antigens on the reproductive
performance of women with SRM."
However Dr Christiansen believes his theory is probably correct because he
has conducted two placebo-controlled trials in which infusions of
intravenous immunoglobulin have been given to women with SRM to try to make
their immune systems tolerate the male-specific antigens. This treatment
increased the live birth rate by a factor of 2.3, whereas no effect could be
detected in women who had never had a child and who suffered recurrent
miscarriages.
"For many years it has been well-known that pregnancies with boys carry an
increased risk for a long series of obstetrical complications compared with
girl pregnancies. We believe that our research will be able to clarify
whether these complications may be related to immunization against male-
specific antigens. If this turns out to be the case, then I believe that we
already have a quite efficient treatment, as our trials have shown."
Abstract no: O-163 (Tuesday, 15.45hrs CET, Paris room)
Notes
[1] SRM is defined as at least three consecutive miscarriages after a
pregnancy that lasted more than | z***u
发帖数: 263 | 7 "我家老二跟老大中间隔了九岁，倒是很顺利。"
老大女儿，老二儿子，不知道板上还有其他的姐妹们孩子们相差这么多的没？。 | n****8
发帖数: 4141 | 8 跟我家一模一样。mm家老二多大了？
【在 z***u 的大作中提到】
: "我家老二跟老大中间隔了九岁，倒是很顺利。"
: 老大女儿，老二儿子，不知道板上还有其他的姐妹们孩子们相差这么多的没？。
| m*********3
发帖数: 5381 | 9 差15岁的报道
★ 发自iPhone App: ChineseWeb 7.8
【在 z***u 的大作中提到】
: "我家老二跟老大中间隔了九岁，倒是很顺利。"
: 老大女儿，老二儿子，不知道板上还有其他的姐妹们孩子们相差这么多的没？。
| n****8
发帖数: 4141 | 10 哇，太有勇气了！
【在 m*********3 的大作中提到】
: 差15岁的报道
:
: ★ 发自iPhone App: ChineseWeb 7.8
| l****y
发帖数: 375 | 11 哎，我就是想怀老二在十周的时候流掉了。大宝宝男孩
child
Tuesday
Fertility
【在 n****8 的大作中提到】
: July 2003
: From European Society for Human Reproduction and Embryology
: Women are more likely to suffer recurrent miscarriages if their first child
: is a boy
: Madrid, Spain: Women who give birth to a boy as their first child are more
: likely to suffer subsequent miscarriages than women whose first baby is a
: girl, an international conference of fertility experts heard today (Tuesday
: 1 July).
: Dr Ole Christiansen, a consultant registrar at the Rigshospitalet Fertility
: Clinic in Copenhagen, Denmark, told the annual conference of the European
| n****8
发帖数: 4141 | 12 pat pat，有个朋友也是老大男孩中间流产两次后又生了两个女儿。
【在 l****y 的大作中提到】
: 哎，我就是想怀老二在十周的时候流掉了。大宝宝男孩
:
: child
: Tuesday
: Fertility
| e****e
发帖数: 1042 | 13 miscarriage没有什么好伤心的，我34岁第一次怀孕就是miscarriage，后来不到3个月
又意外怀上了，生了老大。老大7个月的时候又怀了老二，老二生的时候我就36了。据
说怀孕都有30%流产的可能，早期流产（小于8周）对身体伤害不大。楼主放宽心！
【在 a******n 的大作中提到】
: 刚刚经历了噩梦般的miscarriage，7周,第一次us没有胎心,然后就自己流掉了，真不知
: 道生二宝还要经历这种磨难.不知道版上有多少mm和我一样,有没有什么办法可以
: prevent?
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