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相关话题的讨论汇总
话题: hiv话题: koronis话题: virus话题: gay话题: drug
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y*****g
发帖数: 1822
1
http://www.gay.net/health-fitness/2011/08/21/scientists-mutate-
SCIENTISTS MUTATE HIV TO DEATH
BY: CHRISTOPHER DONALDSON
8.21.2011
Self-destructive behavior may prove a cure for HIV? A new drug still in
trial stages hopes to eliminate HIV from the body by forcing the virus
to
mutate its entirety to death.
Unlike antiretroviral drugs that suppress the virus—even to
undetectable levels—this one essentially “mutates HIV into oblivion.”
And
if the drug does what Seattle-based Koronis Pharmaceuticals says it
should
do, patients would leave treatment HIV-free.
Fastcompany.com reports: Traditional HIV drugs attempt to keep the
virus in check by preventing it from replicating. But Koronis's KP-1461
uses
a new drug mechanism—dubbed Viral Decay AccelerationT—to insert itself
into the viral genome, increasing the frequency of mutations, until
eventually the virus population collapses. "If you think of HIV as a
house
made of two by fours, and the genetic backbone of the virus as the
foundation of that house, [the drug mechanism] replaces the two by fours
with toothpicks, and eventually the house comes crashing down," says Dr.
Mark G. Fromhold, VP of Manufacturing and Business Development at
Koronis.
So far, Koronis researchers have only been able to use this method
to
kill HIV in the lab; decimating HIV in the human body will be much
harder.
But there is hope. In the company's recent Phase 2 clinical trial,
patients
experienced an increase in the mutation frequency of the virus (the 124-
day
trial was too short to see any statistically significant drops in viral
load
, however). And all of Koronis's clinical trials thus far have consisted
of
monotherapy--patients only take KP-1461 without any other drug--even
though
the company believes that KP-1461 may work better in combination with
currently used antiretrovirals.
这种药物会否也同时对人体有害 ?
y*****g
发帖数: 1822
2
http://www.gay.net/gay-away/2011/08/25/provincetown-mass-most-g
http://www3.law.ucla.edu/williamsinstitute/home.html
PROVINCETOWN, MASS.: MOST GAY COUPLES IN AMERICA
BY: BRODIE SCOTT
8.25.2011
As the release of U.S. Census data for 2010 ends, the city with the highest
proportion of same-sex couples is none other than favorite gay hotspot,
Provincetown, Mass.
Provincetown has 163 same-sex couples per 1,000 households, topping Wilton
Manors, Fla., a Fort Lauderdale suburb, according to an analysis of census
information by the Williams Institute.
Palm Springs, California, another gay mecca popular for decades, previously
held the prestigious title.
Interestingly, according to Advocate.com’s Trudy Ring, “if D.C. is counted
as a state rather than a city, it’s the nation’s gayest state, with 19
gay couples per 1,000 households. Among actual states, though, the top one
is Vermont, with 10.9 per 1,000, followed by Massachusetts with 10.2 and
California with 9.9.”
想知道: 这样的调查也是否包括一些已同居多年, 但没有正式结婚注册的同性伴侣?
是否 Massachusetts 在同性就业, 同性配偶福利, 及其他社会待遇比其他地方较好?
y*****g
发帖数: 1822
3
http://www.gay.net/news/2011/08/23/breaking-news-bisexual-men-e
BREAKING NEWS: BISEXUAL MEN EXIST!
BY: JOE THOMPSON
8.23.2011
Bisexuals. It's a label that can cause great controversy among gay and
straight folk alike. Some people believe they're like unicorns—mythic
creatures living in a magical land of rainbows as long as it suits their
sexual needs; or, to put it more bluntly, they think these people are gay,
but they don't want to admit it to themselves. Others suspect it varies
between the sexes: Women are more sexually fluid and can go both ways
without necessarily falling into either camp, while men are more rigid in
their "gay" or "straight" identification. Indeed, researchers at
Northwestern University published a study in 2005 that stated “with respect
to sexual arousal and attraction, it remains to be shown that male
bisexuality exists.”
Needless to say, if you're a self-identified bisexual man, these statements
can really piss you off.
Well, great news, guys! In an unusual scientific about-face, now researchers
at Northwestern have found evidence that some self-identified bisexual men
are actually aroused by both men AND women.
Whew!
According to the New York Times, researchers for this new study relied on
more stringent criteria for selecting participants. First, the researchers
recruited subjects from online venues specifically catering to bisexuals. "
They also required participants to have had sexual experiences with at least
two people of each sex and a romantic relationship of at least three months
with at least one person of each sex." This is different from the 2005
study, where guys were recruited "through advertisements in gay-oriented and
alternative publications and were identified as heterosexual, bisexual or
homosexual based on responses to a standard questionnaire."
Once the male subjects were found, they watched "videos of male and female
same-sex intimacy" (In our country, we call it "porn.") while sensors
monitored their erectile responses. The new study found that bisexual men
responded to both the male and female videos, while gay and straight men in
the study did not.
Allen Rosenthal, the lead author of the new Northwestern study and a
doctoral student in psychology at the university had a great response. He
said, “Someone who is bisexual might say, ‘Well, duh!’ But this will be
validating to a lot of bisexual men who had heard about the earlier work and
felt that scientists weren’t getting them.”
At this point some gay readers will be wondering why this matters, but
consider this: How would you feel if lots of people—gay and straight—said
you didn't exist? Or said you were just confused. Or a whore.
Dr. Lisa Diamond, a psychology professor at the University of Utah and an
expert on sexual orientation, says something similar in the article: “I’ve
interviewed a lot of individuals about how invalidating it is when their
own family members think they’re confused or going through a stage or in
denial. These converging lines of evidence, using different methods and
stimuli, give us the scientific confidence to say this is something real.”
However, she also notes that testing sexual arousal in the lab isn't a
perfect way to examine sexual orientation or identity. “Sexual arousal is a
very complicated thing,” she said. “The real phenomenon in day-to-day
life is extraordinarily messy and multifactorial.”
在文章中的第一段: Women are more sexually fluid and can go both ways
without necessarily falling into either camp, while men are more rigid in
their "gay" or "straight" identification.
这是为什么呢?
另於, 你们也会否认同这一说法?

In an interview with Diva magazine in October 2004, she( Björk ) said:
" I think everyone's bisexual to some degree or another; it's just a
question of whether or not you choose to recognise it and embrace it.
Personally, I think choosing between men and women is like choosing between
cake and ice cream. You'd be daft not to try both when there are so many
different flavours. "
http://en.wikipedia.org/wiki/Bj%C3%B6rk
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相关话题的讨论汇总
话题: hiv话题: koronis话题: virus话题: gay话题: drug