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发帖数: 712 | 1 Identifying Interactions
To detect interactions at microarray features, scientists must label the test
sample in such a way that an appropriate instrument can recog- nize it. Since
the minute size of microarray fea- tures limits the amount of material that c
an be located at any feature, detection methods must be extremely sensitive.
Other than a few low-end systems that use radioactive or chemiluminescent tag
ging, most microarrays use fluorescent tags as their means of identification,
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发帖数: 712 | 2 The GoaL of Standardization
A group at the NHGRI, headed by imaging scien- tist Yidong Chen, is developin
g software that will help to interpret the huge trove of data that microarray
s yield. "We're building a Vind of fin- gerprint record against which to comp
are new array data," explains Chen. "We're at a very, very preliminary stage,
seeing if we can derive any- thing from the'fingerprints' of specific cancers
. At the moment, we're concentrating on breast can cer, prostate cancer, and
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