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Science版 - New Lens Offers Scientist A Brighter Outlook
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话题: mesolens话题: microscope话题: lens话题: confocal话题: outlook
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http://www.sciencemag.org/content/335/6076/1562.summary?ref=top
Since 2000, Brad Amos, inventor of the laser scanning confocal microscope,
has been working on the "Mesolens," a lens capable of capturing a similar
level of detail as a confocal alone, but on a far larger scale. Where
existing microscopes have lenses up to 3 centimeters long, the Mesolens is a
massive half a meter, which means it can capture a specimen as big as a
mouse embryo in a single shot. And whereas a confocal microscope can view up
to 0.22 micrometers below the surface of a specimen, provided it is
translucent enough, the Mesolens plumbs depths of up to 3 millimeters. The
final effect is a 3D picture that allows one to zoom in as far as the level
of the cell. The microscope could save biologists the effort of patching
together hundreds of small high-resolution images if they want a larger one.
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