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发帖数: 302 | 1 1. Identification of antigenic determinant peptides and synthetic peptide
combinatorial libraries
Since peptide vaccines must contain B-cell/T-cell recognized epitopes, it is
crucial to identify them. So far several methods have been used to identify
such epitopes. If the amino acid sequence of a protein antigen is known,
overlapping peptides can be synthesized and screened as targets for B cells,
MHC class I molecules/CTL cells (typically 8-10 amino acids) and MHC II
molecules/helper T cells (t |
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