g*********5
发帖数: 2533 | 1 It depends.
some antibodies I put -20C and take out more than five times and work.
and usually rabbit antibodies are stable than mouse antibodies.
and if you use Licor system, azide is ok.
reuse |
|
B*****e
发帖数: 1005 | 2 Thank you for your kind reply.
IgG content of Antibody may not be equal to purified IgG,
Why don't calculate fold enrichment relative to KO cell line using same
antibody?
2. I would say enrichment folds instead of fold enrichment. I should
calculate folds relative to normal serum
control when antisera are used or IgG control when purified IgG antibodies
are used, which means every
single sample must have a normal serum or IgG control, which makes me sick.
So I often times use non
related DNA re... 阅读全帖 |
|
p*******6
发帖数: 42 | 3 最近作的实验要选择性的在几种细胞混合中stain Bovine Aotic endothelial cell
for Von Willebrand factor. 做了好多次都没有成功.要么根本没有染色,要么提高抗
体浓度后几种不同细胞都被染色而且荧光强度在显微镜照片上根本看不出任何差别,估
计是nonspecific binding of 2nd Ab. 我一直怀疑是primary antibody 的问题.有没
有人曾经做过类似的实验用Von Willebrand factor antibody for Bovine Aotic
endothelial cell. 能不能告诉我你用那个公司的Von Willebrand factor antibody.
多谢! |
|
b******r
发帖数: 111 | 4 Note: NHEs is membrane proteins that transmembrane 12 times. NHE5 is
localized to the plasma membrane;NHE6-9 reside on organellar membranes(
endosome,Golgi);
1. pcDNA transfects NHE5-9 through Fugene 6(ratio is 3 uL of Fugene/2 ug of
DNA) in 293 cells. After three days,collect cells.
2. Cold PBS washes cells. Add 150 uL of lysis buffer(final concentration:
50mM Tris pH7.4, 150mM NaCl, 1% triton, 0.1% sds, cocktail inhibitor)
into each well of 6-well plate. Scrape cells.
3. The lysate gets st... 阅读全帖 |
|
a**********s
发帖数: 8 | 5 说下自己的经验
首先建议用millipore（就是upstate，他们的histone antibody挺好用）的antibodies。
但现在不一定是antibodies的问题，有没有已知的某些gene promoter区域会有你要看
的transcription factor的binding site？你可以先看看在那些区域有没有positive的
binding，这样就可以大致判断你的IP是不是成功的。 |
|
p***i
发帖数: 96 | 6 我用的是CAMKII Cre 老鼠与我的flox老鼠杂交，希望只在forbrain区knockdown我的
gene. 目前得到了Cre Hetero/flox hetero还有Cre homo/flox hetero.
请问如何检测knock down efficiency呢？
1. take forbrain, extract genome, RT PCR
2. perfuse brain, immunostain brain sections with antibody against my gene
of interest. Can I costain with anti Cre antibody? If so, where can I buy a
good one?
3. DAB staining brain sections using antibody against my gene of interest.
请问一般Cre 的knock down efficiency 是多高？ Cre homo or hetero 会有很大区别
吗？
谢谢 |
|
c******i
发帖数: 137 | 7 i guess the problem is staining of antibody is not even. Could you immerse
the membrane in antibody solution, and shake at 4c overnight? also shake in
2nd antibody. |
|
y******8
发帖数: 1764 | 8 Anything extracellular is a potential antigen. Pure pSer antibody in the
animal would develop autoimmune diseases.
So, the pSer antibodies on market are not agaist pure pSer, and are always
context dependent.
If you have a clear target protein, just develop a site specific antibody.
Other wise, p32 is not bad to try since majority of phospho signal comes
from pSer.
are
some
to
with
ourselves
specific |
|
q*****n
发帖数: 331 | 9 Many antibodies (which Abcam sells) are not produced by Abcam.Abcam, and
several others, are more like dealers. They buy bulk antibodies from other
vendors, and re-sell them in small aliquots to make money. Their insert
figures could be from another company. For instance, one antibody was made
by a very small company, and several vendors including Abcam purchase bulk
amount and re-sell it. The initial quality testing data was provided by that
small company. That is why you see the same insert fi... 阅读全帖 |
|
r***n
发帖数: 52 | 10 做IP的negative control一般用isotype control,就是和IP的antibody一样的species,
right?现在我做的IP用的是cell signaling rabbit antibody (polyclonal),
negative control用的是santa cruz的 normal rabbit IgG, 这个有很多的reference
paper引用,看文章上都很干净。但是，我做的结果就是IgG control总有protein of
interest,量和IP的一样多， 这个蛋白是用mouse Ab检测的，MW是90，所以不可能是重
链。奇怪的是，当我检测IP的那个protein (cell signaling),根据说明要4度过夜，结
果发现上次检测的IgG control的目的蛋白量减少了，但不是完全没有，因为我这两个
蛋白都是用ECL检测的，就是说上次检测蛋白的信号还在。但是我又用anti-mouse的二
抗做ECL，IgG control和IP的量又是一样。
这是怎么回事？
还有，有谁知道 cell signaling的Ab用多少... 阅读全帖 |
|
r***n
发帖数: 52 | 11 做IP的negative control一般用isotype control,就是和IP的antibody一样的species,
right?现在我做的IP用的是cell signaling rabbit antibody (polyclonal),
negative control用的是santa cruz的 normal rabbit IgG, 这个有很多的reference
paper引用,看文章上都很干净。但是，我做的结果就是IgG control总有protein of
interest,量和IP的一样多， 这个蛋白是用mouse Ab检测的，MW是90，所以不可能是重
链。奇怪的是，当我检测IP的那个protein (cell signaling),根据说明要4度过夜，结
果发现上次检测的IgG control的目的蛋白量减少了，但不是完全没有，因为我这两个
蛋白都是用ECL检测的，就是说上次检测蛋白的信号还在。但是我又用anti-mouse的二
抗做ECL，IgG control和IP的量又是一样。
这是怎么回事？
还有，有谁知道 cell signaling的Ab用多少... 阅读全帖 |
|
c*******d
发帖数: 192 | 12 The Shapiro Laboratory at Columbia University in New York City, working
together with the NIH Vaccine Research Center (VRC), in Bethesda, MD, seeks
a postdoctoral or staff scientist-level researcher in computational biology
and bioinformatics. Work will involve analyses of high-throughput 454
antibody sequences from HIV infected patients. The goal is to understand
the maturation of these antibodies from their genomically-encoded precursors
in order to inform rational vaccine development. (See... 阅读全帖 |
|
h********n
发帖数: 4079 | 13 blocking peptide, which can bind with the antibody. You can add the
peptide with the antibody to stain a positive sample. If the signal
disappears, it means the antibody has good specificity. My phd boss think
this is very important. |
|
M*****e
发帖数: 279 | 14 我有类似的经历：检测不到一个ATCC cell line 的 beta-actin。
Cell line: SW780 (human urothelial carcinoma).
I bought this cell line twice from ATCC, but I could not detect beta-actin
at all. The expression of beta-actin as shown by Western blot in this cell
line was reported in the literature.
I could detect GAPDH in this cell line.
I could use the same beta-actin antibody (Sigma) to detect beta-actin in
other human cell lines (urothelial and non-urothelial carcinoma) using the
same antibody (Sigma).
I don't thin... 阅读全帖 |
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k****n
发帖数: 42 | 15 本人刚开始做CHIP。 现在遇到一情况：虽然我的INPUT各种PRIMERS的CT相似，但是我
的IGG在不同的PRIMERS中CT相差非常大。
实际的数据如下：
negative control primers: Igg DeltaDelta CT: 0.000126; my antibody
DeltaDelta CT: 0.002845.
positive control primers: Igg DeltaDelta CT: 0.00031; my antibody
DeltaDelta CT: 0.055.
my sample primers: Igg DeltaDelta CT: 0.035; my antibody DeltaDelta CT：0.51
我觉得不是PRIMERS的EFFICIENCY的问题，毕竟INPUT的CT很相似。
所以我不知道这个数据是否正常。还有，最后怎么做数据分析？ 也就是要发PAPER的话
，该如何处理这些数据？ 谢谢了！ |
|
g*********5
发帖数: 2533 | 16 I am studing a protein Nrf2 now, and predict size should be 68kD, but it is
100-120 kDa on trisglycine gels...
and I know this protein is phosphyralted protein, but different is so big.
and santa cruz antibody give a lot band with western, and even that a lot
ppls use santa cluz antibody do immunofluoresence...
and some labs use their homemade protein purified antibody and go 68kDa band
... and some ppl said Nrf2 at 53kDa on their paper...
confuse me.... |
|
g*********3
发帖数: 177 | 17 我比较同意你说的三大块~ 另外ENCODE稍微做了下和各种SNP的overlapping，另外试着
test了一些很basic的假说~
ENCODE的histone antibody个人认为是可靠的，他们有好几篇paper(包括此前的专门一
篇test antibody的paper)是专门test antibody specificity的，基于WB和MS，QPCR..
.我觉得就差不多了~
我觉得你说的数据差异大，应该是生物学的本质...
另外，我们可能还需要更多的数据来告诉那些combinations of histone marks才是真
正的informative...这个在ENCODE里才刚刚开始~ |
|
s*****g
发帖数: 87 | 18 最近要检测一个蛋白的表达量，但是这个蛋白在细胞内的表达量很低
请教各位达人，以下哪个方法更灵敏，或者说更有可能检测到蛋白的表达？
1. Flow cytometry after treatment of FITC-conjugated primary antibody.
2. Western blot analysis using primary antibody and HRP-conjugated secondary
antibody
谢谢！ |
|
s*******2
发帖数: 598 | 19 1st antibody from SigmaA 5316, 2nd antibody anti mouse IgG from Cell
Signaling #
7076S, all produced in 2012.
Are these 2 antibodies not match well? |
|
q******g
发帖数: 3858 | 20 Andraka cultured MIA PaCa cells, from a commercial pancreatic carcinoma cell
line, which overexpress mesothelin, a biomarker for pancreatic cancer. The
mesothelin was isolated, concentrated and quantified with ELISA.[6] After
optimization with the Western Blot assay, the human mesothelin-specific
antibodies were mixed with single walled carbon nanotubes and used to coat
strips of ordinary filter paper. This made the paper conductive. The optimal
layering was determined using a scanning electron ... 阅读全帖 |
|
h**********r
发帖数: 671 | 21 必须是pESC系列。
当时我还问大家要不要加kozak序列，也没说出个所以然来。后来我终于等到了客服的
答复。下面就是：
The GAL1 and GAL10 yeast promoters from the pESC-Leu vector have the FLAG or
the MYC epitopes in the two MCS of the vector. Both include ATG codons at
the 5’ end of the FLAG and the MYC epitopes. If you clone into the Bgl II
or the Xho I site in frame with the ATG of the epitope tag, you will have
the start codon, kozak sequence and should get good expression of your N-
tagged protein. If you need the epitope tag at the C-terminal, ... 阅读全帖 |
|
d****i
发帖数: 2346 | 22 Warning: BSA and dry milk may contain IgG which will react with this
antibody. Use of BSA and/or dry milk to block or dilute this antibody may
increase background and/or reduce secondary antibody titer.
http://www.jacksonimmuno.com/catalog/CatPages/rblc.asp |
|
M********r
发帖数: 142 | 23 pls refer http://www.nature.com/ncb/journal/v15/n4/full/ncb2702.html?WT.ec_id=NCB-201304
most important is ab.
Yi Zhang used F7452 sigma. nobody won't trust yi zhang ..
ChIP-seq sample preparation.
For Kdm2b ChIP, Kdm2b Flag-tag knock-in mESCs were fixed with 2 mM
ethylene glycol bis(succinimidylsuccinate) (Thermo Scientific) for 1 h
, followed by 10 min in 1% formaldehyde and 5 min in 0.125
;M glycine to sequence the reaction. Cells were lysed in 1% SDS, 10 ... 阅读全帖 |
|
t**l
发帖数: 109 | 24 你的1st and 2nd antibody 还有样品是什么种的，血清中可能会有IgG吧，2nd
antibody应该是那种light chain specific
50KDA的位置正好是IgG heavy chain 的位置。
还有就是rabbit的antibody要比goat的好用。goat很脏，普通的BSA和MILK根本block不
了。 |
|
n***w
发帖数: 2405 | 25 okay. so in this case, maybe your HSP90 antibody or other antibodies don't
work well in IP conditions?
I have met multiple occasions where IP only goes one-way... :-/ It could
just be antibody issue. You can try cross link. If that doesn't work, then
move on... |
|
B*****l
发帖数: 1078 | 26 Well all their antibodies r bang for the buck.
Depending on what antibody u r looking for and u pretty much get what u pay
for. But still better than alot of small companies out there charging
premium for shitty quality antibodies.
Hell if u have money to spare just go with companies like cell sig. |
|
a****b
发帖数: 48 | 27 谢谢各位的帮忙，想仔细学习下面3篇文章： [email protected]
/* */
1） Therapeutic Antibodies in HIV Treatment - Classical Approaches to Novel
Advances
Author(s): Irene A. Abela, Lucy Reynell and Alexandra Trkola
Pages 3754-3766 (13)
Current Pharmaceutical Design
VOLUME: 16
ISSUE: 33
DOI: 10.2174/138161210794079245
2） The FcγR of Humans and Non-human Primates and Their Interaction with
IgG: Implications for Induction of Inflammation, Resistance to Infection and
the Use of Therapeutic Monoclonal Antibodies
P.... 阅读全帖 |
|
C****3
发帖数: 162 | 28 Head of Formulation development of Antibody drugs， if interested, please
contact
Vic Li, Cellphone: +86 151 2101 2330 eMail: [email protected]
/* */
-Preformulation, formulation development, and process development
activitiesthat supports the drug development and technical transfer
of clinical andcommercial antibody products.
-Development, transfer, process characterization, and validation of aseptic
vial,syringe and drug delivery devices.
-Lead and train the team to acc... 阅读全帖 |
|
k*****n
发帖数: 323 | 29
e, just another antibody against Rat IgG, like rabbit @ Rat, or Goat @ Rat,
you can use Protein G bead incubate with either one bridge antibody for 1h @
4C first, wash once, then add Rat @ HA antibody, incubate for another 2h @
4C. |
|
k*****n
发帖数: 323 | 30
e, just another antibody against Rat IgG, like rabbit @ Rat, or Goat @ Rat,
you can use Protein G bead incubate with either one bridge antibody for 1h @
4C first, wash once, then add Rat @ HA antibody, incubate for another 2h @
4C. |
|
O********4
发帖数: 113 | 31 是真偷了有用的东西，还是杀一儆百？
Two GlaxoSmithKline scientists and three others were charged by a federal
grand jury in Philadelphia on Wednesday with conspiracy to steal promising
cancer research secrets from the pharmaceutical giant and market them to
companies in China backed by the Chinese government.
U.S. Attorney Zane David Memeger said Yu Xue, 45, of Wayne; Tao Li, 42, and
Yan Mei, 36, both of Nanjing China; Tian Xue, 45, of Charlotte, N.C.; and
Lucy Xi, 38, of West Lake Village, Calif., were named in ... 阅读全帖 |
|
k*****n
发帖数: 323 | 32 and using Pol II antibody as control. there is no TF antibodies can work
better than Pol II, if you can still get huge amount DNA, then is the
protocol or bead issue. if not, then your own antibody has issue. without
right control, it is hard for troubleshooting. best |
|
发帖数: 1 | 33 I ask for paper, due to unavailability of downloading in our hospital.
J Heart Lung Transplant. 2016 May 6. pii: S1053-2498(16)30110-3. doi: 10.
1016/j.healun.2016.04.007. [Epub ahead of print]
The effect of timing and graft dysfunction on survival and cardiac allograft
vasculopathy in antibody-mediated rejection.
Clerkin KJ1, Restaino SW1, Zorn E2, Vasilescu ER3, Marboe CC3, Mancini DM4.
Author information
Abstract
BACKGROUND:
Antibody-mediated rejection (AMR) has been associated with increased... 阅读全帖 |
|
f***x
发帖数: 1524 | 34 hybridomas筛的是🐭源抗体，需要人源化。前期需要免疫动物。immune
response 是个问题。优点是有in Vivo quality control,一般不再需要affinity
Maturation and solubility/stability optimization.
相比较，display 可以从人工库筛，库可以很大(10e7-10e11)，用时短，不用考虑免疫
问题。但是往往需要affinity maturation.
Phage display 筛fragment.
yeast display可以 筛full length antibody.
方法上，phage display 简单。主要是Elisa and affinity binding/washing.
yeast display 用到FACS,可以对筛选有很好的控制，同时筛Antibody expression/
stability 和antibody-antigen binding. |
|
z*t
发帖数: 863 | 35 受教了！您怎么看alpaca里搞得nanobody?
：hybridomas筛的是🐭源抗体，需要人源化。前期需要免疫动物。immune
：response 是个问题。优点是有in Vivo quality control,一般不再需要affinity
：Maturation and solubility/stability optimization.
：相比较，display 可以从人工库筛，库可以很大(10e7-10e11)，用时短，不用考虑免
疫问题。但是往往需要affinity maturation.
：Phage display 筛fragment.
：yeast display可以 筛full length antibody.
：方法上，phage display 简单。主要是Elisa and affinity binding/washing.
：yeast display 用到FACS,可以对筛选有很好的控制，同时筛Antibody expression/
：stability 和antibody-antigen binding. |
|
z*******o
发帖数: 1794 | 36 我观察的，隔壁办公室的就是专门做antibody binding的，他们那做antibody和target
的结合实验是每天的常规工作，而且都要备案准备交FDA的，至少我们这没有看到他们
整结晶看蛋白结构，整个下游表达分析纯化没见哪个组做结晶看结构的。你说借鉴蛋白
结构是可以，但越到下游越不能随便借鉴，尤其是申报FDA的资料，最好自己公司搞出
来。楼里有人说在公司做结构研究，那一定是做research那边的，而且一定是大公司的
。但你说就凭结构设计antibody靠谱还是display筛库靠谱呢？我想公司的vp和ceo已经
给出答案了。 |
|
V******1
发帖数: 8 | 37 作为一个没做过膜蛋白的伪structure biologist，赞一下专业回答。
再补充一点生物大分子的。结构可能对于大分子比如抗体的指导作用没有receptor/
ligand或者enzyme/substrate那么看起来那么直接，但也有很大帮助。比如知道target
的结构，就可以有针对性地display更感兴趣的epitope，尤其是那些non-linear的
epitope单单根据序列是没法预测的。反过来说也可以突变掉unwanted epitope来避免
screen到不想要的抗体。拿到antibody/antigen complex的结构，可以根据结构做有针
对性的affinity maturation来进一步优化抗体。design bi-specific甚至tri-
specific antibody，需要考虑几个target epitope在空间上的位置。做vaccine的，可
以根据结构来design engineer的antigen，使之更有效地产生neutralizing antibody
。还有找到一个好的抗体，patent的时候也得知道epitope的不是，虽... 阅读全帖 |
|
B******1
发帖数: 9094 | 38 You are contradicting yourself.
You claimed that "naturally produced" antibodies are superb and should not
include those generated by external stimulus. Therefore, the antibodies
generated by traditional Chinese medicine are as bad as those generated by
vaccination.
Furthermore, the word antibody is a term not often used by any traditional
Chinese medical doctors. Who taught you the way to proscribe traditional
Chinese medicine? |
|
k**e
发帖数: 2728 | 39 ☆─────────────────────────────────────☆
jjmaji (jjmaji) 于 (Thu Dec 31 15:15:32 2009, 美东) 提到:
和LD结婚多年，结婚时知道LD表面抗原阳性也没在意。
我以前也从未做过乙肝检查，只知道大学的时候还献过
血。
我最近做了一次检查，请大家帮我看看lab results.
我的family doctor也不是很懂，说不出所以然。
Hepatitis B Surface Antigen -- non-reactive
Hepatitis B Core Antibody IGM -- index <0.05
Hepatitis B Core Antibody Total -- reactive
Hepatitis B Surface Antibody -- index=54.44
大家能不能给我解释一下结果?
多谢！
☆─────────────────────────────────────☆
againstwind (逆风而行) 于 (Thu Dec 31 15:52:33 2009, |
|
d*********e
发帖数: 15 | 40 I used UV280 nm, Bradford assay as well as running a SDS-Gel, all leading to
same concentration.
I know antibody protein expression and purification is very expensive, but
do you think Genentech is trying to save the cost by using less amount of
antibody ? After all, it is vey unlikely that patients or doctors would
find out the true quantity of the antibody. It is only us, the biology
researchers, who would happen to find out the truth, by accident.
Do we have responsibility to ask Genentech |
|
C****3
发帖数: 162 | 41 Head of Formulation development of Antibody drugs， if interested, please
contact
Vic Li, Cellphone: +86 151 2101 2330 eMail: [email protected]
/* */
-Preformulation, formulation development, and process development
activitiesthat supports the drug development and technical transfer
of clinical andcommercial antibody products.
-Development, transfer, process characterization, and validation of aseptic
vial,syringe and drug delivery devices.
-Lead and train the team to acc... 阅读全帖 |
|
S****u
发帖数: 42 | 42 来自主题: Pharmaceutical版 - 无标题 Please apply from the Pfizer Website:
https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---
California---Rinat/Scientist--non-PhD---Protein-Engineering_4692599
Pfizer -CID
Pfizer Cancer Immunology Discovery (CID) is a South San Francisco
biotechnology unit within the Oncology division of Pfizer Worldwide Research
& Development, dedicated to doing its part to fulfill Pfizer's mission of
working together for a healthier world. CID is dedicated to developing new
protein and cell-b... 阅读全帖 |
|
o******x
发帖数: 6 | 43 Mostly this is an article mixed with right with wrong.
1. SARS is a RNA virus, that's right, so do AIDS. But AIDS boost significant
antibody response, even at very early stage of infection. Right, the most
reliable way to detect AIDS is still to measure antibody level in patients.
And this antibody reaction is very efficient to kill virus. That's reason
patients can survive years even without any treatment.
2. There are several types of virus, including DNA virus, RNA virus. The
typical life cyc |
|
z*******2
发帖数: 2643 | 44 Complex Vitamin B's (B-12) and Vitamin C can prevent cold and flu.
your test is hard to do because of the following reasons.
1. It's difficult to control the flow of flu and cold virus to children. Flu
virus affects children randomly. You can not force one type of flu to
affect a particular group of testers simultaneously.
2. It's hard to know whether a child has had the virus in the past and
whether he/she has already got antibody in his/her body. If the child has
already got this type of antib... 阅读全帖 |
|
V*****G
发帖数: 337 | 45 Nice, both of your differential are hard to come up with. LouZhu is playing
tough ball, don't mention rash at all in Hx. I will add rickettsial
diseases:
Endemic typhus (fleas)––R. typhi. centrally and spreads out:
Epidemic typhus (human body louse)––R. prowazekii. Typhus rash starts on
the Trunk.”
Ehrlichiosis (tick)––Ehrlichia.
Q fever (inhaled aerosols)––Coxiella burnetii.
Malaria needs to be ruled out too (copyright of chestnut, although I thought about this too).
Workup and management:
CB... 阅读全帖 |
|
I****a
发帖数: 407 | 46 From story, there is not enough information to say there is APS. As A++
pointed out, the antibody testing are very frequently falsely positive
especially in infection and renal failure setting and if the antibody titers
are low positive. He has a stroke like symptoms but CNS vasculitis could
also cause this. Overall my impression is that this guys has an autoimmune
process with antibody messing around the kidneys and perhaps CNS, bone
marrow. The PCP infection is secondary.
If all his serology t... 阅读全帖 |
|
b******a
发帖数: 704 | 47 Most likely, this baby has been diagnosed with primary autoimmune
neutropenia, which usually linked with a good prognosis.
Here is what I could copy and paste from internet as a first grade in
Medicine, lol.
Autoimmune neutropenia (AIN) is caused by granulocyte-specific antibodies.
In most cases, AIN is not associated with any other illness or underlying
disease, and therefore is called primary AIN if anti-Granulocyte specific
antibodies are detected, or chronic benign neutropenia (CBN) if ther... 阅读全帖 |
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n***a
发帖数: 1373 | 48 来自主题: Medicalpractice版 - 甲亢 求助 This is what I think. The TSI antibody is useful for the diagnosis of Graves
' disease , but not these two antibodies. If this antibody is positive, then
pretty much Graves disease. If negative, you still need a radioactive
iodine uptake study to differentiate from thyroiditis.
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y*****l
发帖数: 5997 | 49 药股: Progenics Pharmaceuticals Inc PGNX:NASDAQ
Progenics Awarded $4.1 Million NIH Grant to Advance Novel C. Difficile
Antibody Therapy
Wednesday 10/06/2010 9:00 AM ET - Businesswire
Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) today announced the award of
a grant totaling $4,143,652 from the National Institutes of Health (NIH) for
Progenics' program to develop novel monoclonal antibodies to treat
Clostridium difficile (C. difficile) infection. C. difficile is a bacterium
that represents the lea... 阅读全帖 |
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y*****l
发帖数: 5997 | 50 12/12. Have spt @ 1.75.
YM BioSciences to Report Updated Phase I/II Data for CYT387 at ASH 2011
YM BioSciences Inc. (NYSE Amex: YMI, TSX: YM), today announced it would
report updated results from its Phase I/II myelofibrosis study of CYT387, a
JAK1/JAK2 inhibitor, in a poster session to be held from 6:00pm - 8:00pm on
Monday, December 12th at the 53rd Annual Meeting of the American Society of
Hematology (ASH) being held in San Diego, California. The Company also
reported updated results today fr... 阅读全帖 |
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