s**i
发帖数: 4448 | 3 When injected into eight-cell embryos or
blastocysts, CiPSCs were capable of integra-
tion into organs of all three germ layers, including
gonads and transmission to subsequent generations
(Fig.3,BtoE,andfig.S16).Unlikechimericmice
generated from iPSCs induced by transcription
factors including
c-Myc
(
14
), the chimeric mice
generated from CiPSCs were 100% viable and
apparently healthy for up to 6 months (Fig. 3F).
These observations suggest that the CiPSCs were
fully reprogrammed into pluripotency (table S3
只是整合到胚胎里去了嘛。 |
