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发帖数: 258 | 1 祝大家中秋节快乐！
Optoelectromechanical Multimodal Biosensor with Graphene Active Region
http://pubs.acs.org/doi/abs/10.1021/nl502279c
A general, overarching theme in nanotechnology is the integration of
multiple disparate fields to realize novel or expanded functionalities. Here
, we present a graphene enabled, integrated optoelectromechanical device and
demonstrate its utility for biomolecular sensing. We experimentally achieve
an ultrawide linear dynamic sensing range of 5 orders of magnitude of
protein concentration, an improvement over state-of-the-art single mode
nanosensors by approximately 2–3 orders of magnitude, while retaining a
subpicomolar lowest detection limit. Moreover, the ability to monitor and
characterize adsorption events in the full optoelectromechanical space
allows for the extraction of key intrinsic parameters of adsorbates and has
the potential to extend the capabilities of nanosensors beyond the
traditional binary-valued test for a single type of molecule. This could
have significant implications for molecular detection applications at
variable concentrations, such as early disease detection in biomedical
diagnostics. |
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