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发帖数: 3896 | 1 又是一连两篇Science文章：
http://m.sciencemag.org/content/338/6114/1622
Science 21 December 2012:
Vol. 338 no. 6114 pp. 1622-1626
DOI: 10.1126/science.1229164
Report
Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a
Single Human Cell
Authors
Chenghang Zong1,*,
Sijia Lu1,*,†,
Alec R. Chapman1,2,*,
X. Sunney Xie1,‡
1Department of Chemistry and Chemical Biology, Harvard University, Cambridge
, MA 02138, USA.
2Program in Biophysics, Harvard University, Cambridge, MA 02138, USA.
↵‡To whom correspondence should be addressed. E-mail: xie@
chemistry.harvard.edu
↵* These authors contributed equally to the work.
↵† Present address: Yikon Genomics, 1 China Medical City Avenue,
TQB Building, 5th floor, Taizhou, Jiangsu, China.
http://m.sciencemag.org/content/338/6114/1627
Science 21 December 2012:
Vol. 338 no. 6114 pp. 1627-1630
DOI: 10.1126/science.1229112
Report
Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-
Genome Sequencing
Authors
Sijia Lu1,*,†,
Chenghang Zong1,*,
Wei Fan2,*,
Mingyu Yang2,*,
Jinsen Li2,
Alec R. Chapman1,3,
Ping Zhu2,
Xuesong Hu2,
Liya Xu2,
Liying Yan4,5,
Fan Bai2,
Jie Qiao4,5,
Fuchou Tang2,
Ruiqiang Li2,6,‡,
X. Sunney Xie1,2,‡
1Department of Chemistry and Chemical Biology, Harvard University, Cambridge
, MA 02138, USA.
2Biodynamic Optical Imaging Center, School of Life Sciences, Peking
University, Beijing 100871, P. R. China.
3Program in Biophysics, Harvard University, Cambridge, MA 02138, USA.
4Center for Reproductive Medicine, Third Hospital, Peking University,
Beijing 100191, P. R. China.
5Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing
100191, P. R. China.
6Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking
University, Beijing 100871, P. R. China.
↵‡To whom correspondence should be addressed. E-mail: lirq@pku.
edu.cn (R.L.); x*[email protected] (X.S.X.)
↵* These authors contributed equally to this work.
↵† Present address: Yikon Genomics, 1 China Medical City Avenue,
TQB Building 5th Floor, Taizhou, Jiangsu, China. |
