x********i
发帖数: 905 | 1 2016 Breakthrough Prize in Life Sciences
The Breakthrough Prize in Life Sciences honors transformative advances
toward understanding living systems and extending human life, with one prize
dedicated to work that contributes to the understanding of Parkinson’s
disease and neurodegenerative disorders.
Edward S. Boyden, Massachusetts Institute of Technology: for the development
and implementation of optogenetics – the programming of neurons to express
light-activated ion channels and pumps, so that their electrical activity
can be controlled by light.
Karl Deisseroth, Stanford University and Howard Hughes Medical Institute:
for the development and implementation of optogenetics – the programming of
neurons to express light-activated ion channels and pumps, so that their
electrical activity can be controlled by light.
John Hardy, University College London: for discovering mutations in the
Amyloid Precursor Protein gene (APP) that cause early onset Alzheimer’s
disease, linking accumulation of APP-derived beta-amyloid peptide to
Alzheimer’s pathogenesis and inspiring new strategies for disease
prevention.
Helen Hobbs, University of Texas Southwestern Medical Center and Howard
Hughes Medical Institute: for the discovery of human genetic variants that
alter the levels and distribution of cholesterol and other lipids, inspiring
new approaches to the prevention of cardiovascular and liver disease.
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology:
for pioneering the sequencing of ancient DNA and ancient genomes, thereby
illuminating the origins of modern humans, our relationships to extinct
relatives such as Neanderthals, and the evolution of human populations and
traits. | s******c
发帖数: 331 | 2 这个奖虽然听起来很山寨，却极其的高大上，是一帮做计算机和网络发家的富豪包括马
云搞的，每个获奖的有3M dollors的巨款，比诺奖有钱多了。 | n****n
发帖数: 492 | 3 I am irritated by the fact the breakthrough award on optogenetics only gave
to Deisseroth and Boyden. Yet, people (I am talking about Peter Hegemann,
Georg Nagel and Ernst Bamberg) who originally identified, cloned, and
functionally characterized Channelrhodopsin were not awarded. Yes,
Deisseroth and Boyden have made substantial contributions in modifying,
optimizing, and popularizing this tool. However, I believe without them
there will be second, third, forth, or more Deisseroth/Boyden coming out.
They are not irreplaceable. Indeed, several groups were not far behind when
they published their Nature Neurosci paper in 2005. By contrast,
optogenetics is not possible without these German scientists' work.
Anyone interested in the history of optogenetics should take a quick look at
2013 brain prize, which is fair.
http://www.thebrainprize.org/flx/prize_winners/prize_winners_20
prize
development
express
【在 x********i 的大作中提到】
: 2016 Breakthrough Prize in Life Sciences
: The Breakthrough Prize in Life Sciences honors transformative advances
: toward understanding living systems and extending human life, with one prize
: dedicated to work that contributes to the understanding of Parkinson’s
: disease and neurodegenerative disorders.
: Edward S. Boyden, Massachusetts Institute of Technology: for the development
: and implementation of optogenetics – the programming of neurons to express
: light-activated ion channels and pumps, so that their electrical activity
: can be controlled by light.
: Karl Deisseroth, Stanford University and Howard Hughes Medical Institute:
| D***a
发帖数: 516 | 4 相当于给了张生家，没给谢灿？
gave
when
【在 n****n 的大作中提到】
: I am irritated by the fact the breakthrough award on optogenetics only gave
: to Deisseroth and Boyden. Yet, people (I am talking about Peter Hegemann,
: Georg Nagel and Ernst Bamberg) who originally identified, cloned, and
: functionally characterized Channelrhodopsin were not awarded. Yes,
: Deisseroth and Boyden have made substantial contributions in modifying,
: optimizing, and popularizing this tool. However, I believe without them
: there will be second, third, forth, or more Deisseroth/Boyden coming out.
: They are not irreplaceable. Indeed, several groups were not far behind when
: they published their Nature Neurosci paper in 2005. By contrast,
: optogenetics is not possible without these German scientists' work.
| x****g
发帖数: 51 | 5 这个好：
Helen Hobbs, University of Texas Southwestern Medical Center and Howard
Hughes Medical Institute: for the discovery of human genetic variants that
alter the levels and distribution of cholesterol and other lipids, inspiring
new approaches to the prevention of cardiovascular and liver disease. | x****g
发帖数: 51 | 6 这个好
Helen Hobbs, University of Texas Southwestern Medical Center and Howard
Hughes Medical Institute: for the discovery of human genetic variants that
alter the levels and distribution of cholesterol and other lipids, inspiring
new approaches to the prevention of cardiovascular and liver disease. | l****y
发帖数: 398 | 7 I guess this award was designed to complement the Nobel. It seems the
Germans will get the Nobel.
[在 neuron (云中漫步) 的大作中提到：]
：I am irritated by the fact the breakthrough award on optogenetics only
gave to Deisseroth and Boyden. Yet, people (I am talking about Peter
Hegemann,
：Georg Nagel and Ernst Bamberg) who originally identified, cloned, and
：........... |
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