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全部话题 - 话题: toxin
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m******5
发帖数: 1383
1
来自主题: Biology版 - Diphtheria Toxin resistant cell line
Dear all:
I am planing to buy a Diphtheria Toxin resistant cell line for the
convenience of expressing a protein embedded in a DTA expressing construct.
I searched around but end up having no idea.
Does anyone know where I can buy them? Thanks alot!!!!!!!!!
-_- if there is a DTA resistant HEK293 cell line would be perfect
k****s
发帖数: 81
2
本人现在的单位不sponsor绿卡了,NIW批准了,当时排期太慢了,本人因为各种原因急
需尽早搞定绿卡,只能努力攒review去争取EB1a了。听说这里牛人很多,特来发帖求助
,先谢谢大家了!
本人研究主要集中在离子通道,电生理方向,用patch clamp,two-electrode
voltage clamp 研究离子通道特性;同时也研究spider toxin及对离子通道的影响。主
要研究Voltage-gated channels 和TRP通道,在current biology,plos one,JCE等上
一作各一片,circulation等挂名作者。恳请有审稿机会而又不需要继续攒review的牛
人帮我推荐啦,谢谢!!
s**********e
发帖数: 2888
3
来自主题: Biology版 - 批评sunnyday同学一下
found an interesting article:
One of the favourite arguments of the pro-GM lobby in support of Bt-toxin GM
crops is that the Bt toxin has been safely used for decades by organic
farmers.
Many thanks to Susan Pusztai for the following information which precisely
delineates the very considerable differences between the use of Bt in
organic farming and the use of the Bt toxin as a transgene in GM crops.
This should be read in conjunction with Arpad Pusztai's recent comments,
posted to the ngin list... 阅读全帖
s*****o
发帖数: 2490
4
我是做杀虫剂毒理的,本版关于bt toxin在epa的风险评估是我最早提供的。关于对bt
toxin的毒理数据和风险评估的解读想和你探讨一下。
第一,bt toxin的acute toxicity的试验用到的剂量上限相当相当的高,EPA的risk
assessment里用到的是3.2mg/g,有的文献里是超过10mg/g,注意这是试验用到的最大
剂量,不是LD50,在这个剂量之下没有一只老鼠死亡。如果你做过oral toxicity就知
道,对小鼠或者大鼠来说这几乎是可以被撑死的剂量了(水的ld50是18mg/g,10mg/g的
水可能都会杀死一定比例的老鼠),这么大的量即使在胃内被降解大部分,也会有相当
多的剂量进入肠道,可是这么大的量没有产生mortality (epa的RA提到没有一只老鼠死
掉),这说明第一种可能,在鼠体内的蛋白酶对bt protoxin的切割是non specific的,
如果有切割的话,产生的active toxin的量相当低;第二种可能,active toxin与受体
的结合是non specific的,如果有的话;第三种可能,酶切和受体结合都是non-s... 阅读全帖
d********a
发帖数: 3698
5

美国现在还没有转基因的小麦和水稻
转基因这种东西在科研上是必须要搞的,但远不到大规模普及的程度。中国来个大跃进
搞到水稻和小麦上让人吃有些急了。
以现在中国社会一切向钱看的风气,大规模搞转基因主食潜在的危险可能远远超过眼前
利益,况且还又是一小部分人的利益。
================================
人体内检测出多种转基因毒素,转基因核心谎言被戳穿
翻译评论:加拿大一个彻底戳穿转基因谎言的划时代重要研究
作者/译者:半解一知半解
评论:鉴于长期以来, 国内外转基因的讨论与推广已严重偏离科学的轨道,成了一个
利益和政治问题,所以, 有必要矫枉过正把这个问题还原回科学的轨道。
不可否认, 转基因技术本身是一种科学, 但同样不可否认,不是所有的科学技术都是
完美无缺、有益无害的,转基因是一种未经严格验证、其安全性还存在很多未知和不确
定性的技术,是一种存在巨大争议和巨大风险的技术,因为这项技术涉及到食品及食品
安全,所以,在实验室进行研究、完善无可质疑,但如果大面积推广,就应该受到质疑
乃至反对。这应该是目前大多数反转基因民众和仁人志士的基本共识。
而国内外转基因势... 阅读全帖
l**********1
发帖数: 5204
6
利用人工智能免疫系 likes CD44 plus Hyaluronan (hyaluronic acid, HA) is a
linear naturally occurring polysaccharide 钓3kDa左右的多肽的鱼
可以不通过分离而直接挑出peptide or protein来特异反应--just matrix two cents.
References:
1)
Erickson M, Stern R.
Chain gangs: new aspects of hyaluronan metabolism.
Biochem Res Int.2012:893947.
//www.ncbi.nlm.nih.gov/pubmed/22216413
and
2)
Chaim OM et al.(2011)
Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes.
Toxins (Basel). 3: 309-344
Abstract
Venomous animals use ... 阅读全帖
X*******8
发帖数: 3895
7
刚才看有人在“请教一个转基因问题”,故把下面一篇文章转过来,没有翻译,有兴趣
的自己看吧。
http://www.holistichealthsecrets.com/alternativehealth/genetica
modified-foods-healthy-to-eat/
Are Genetically Modified Foods Healthy to Eat?
July 14th, 2009adminLeave a commentGo to comments
The topic of Genetically Modified Food (GMOs) can be confusing. On one side
we have big Pharma
companies touting studies that show that Genetically Modified Food is
perfectly safe for consumption. On
the other hand, we have wholistic health groups and speakers s... 阅读全帖
X*******8
发帖数: 3895
8
读读这个吧,没有翻译,有兴趣
的自己看吧。AAEM的人你不因该叫民科了吧?另外,谁把我关于先锋分类的贴删了?每
必要这么害怕吧?
http://www.holistichealthsecrets.com/alternativehealth/genetica
modified-foods-healthy-to-eat/
Are Genetically Modified Foods Healthy to Eat?
July 14th, 2009adminLeave a commentGo to comments
The topic of Genetically Modified Food (GMOs) can be confusing. On one side
we have big Pharma
companies touting studies that show that Genetically Modified Food is
perfectly safe for consumption. On
the other hand, we have wholistic health gr... 阅读全帖
p****o
发帖数: 1100
9
hoho.. 幽默我没有。 无知的大概是你。。
看看下面的 机理吧!
The Bt toxin is so named because it comes from the bacterium Bacillus
thuringiensis. Farmers have used spray formulations of this bacterium on
their crops since the 1920s as a means to control certain insect pests. It
has been widely used in the Americas, Europe and Asia, and it is one of the
pesticides allowed for use in organic farming.
In determining the safety of Bt proteins, it is important to understand how
they work. When consumed by insects, the toxi... 阅读全帖
s********o
发帖数: 3319
10
【 以下文字转载自 MedicalCareer 讨论区 】
发信人: herby (小臭宝), 信区: MedicalCareer
标 题: [合集] 你有生以来做出的最佳临床诊断是什么?
发信站: BBS 未名空间站 (Thu Jun 2 00:01:26 2011, 美东)
☆─────────────────────────────────────☆
Aplusplus (Hakuna Matata) 于 (Sun Mar 27 11:11:49 2011, 美东) 提到:
首先我申明,我放弃我的ignore list, 欢迎所有ID参加。
每个医生护士或者其他相关人员, 无论在中国还是美国, 肯定都有一些case刻骨铭心
。 请大家把你印象最深的一例写出来, 与大家分享。 比方说, 清华男被鉈杀案,
那个中国来的护士就是诊断的关键, 相信本例就是她一辈子也忘不了的诊断。
我觉得这样的讨论有助于大家提高学医热情,丰富医学知识,开拓临床思维, 间接帮
助考版医生复习,准备CS,和 interview. 你要是能从中挑一个case让你PD
impressed,我想我的... 阅读全帖
s********o
发帖数: 3319
11
【 以下文字转载自 MedicalCareer 讨论区 】
发信人: herby (小臭宝), 信区: MedicalCareer
标 题: [合集] 你有生以来做出的最佳临床诊断是什么?
发信站: BBS 未名空间站 (Thu Jun 2 00:01:26 2011, 美东)
☆─────────────────────────────────────☆
Aplusplus (Hakuna Matata) 于 (Sun Mar 27 11:11:49 2011, 美东) 提到:
首先我申明,我放弃我的ignore list, 欢迎所有ID参加。
每个医生护士或者其他相关人员, 无论在中国还是美国, 肯定都有一些case刻骨铭心
。 请大家把你印象最深的一例写出来, 与大家分享。 比方说, 清华男被鉈杀案,
那个中国来的护士就是诊断的关键, 相信本例就是她一辈子也忘不了的诊断。
我觉得这样的讨论有助于大家提高学医热情,丰富医学知识,开拓临床思维, 间接帮
助考版医生复习,准备CS,和 interview. 你要是能从中挑一个case让你PD
impressed,我想我的... 阅读全帖
W*****B
发帖数: 4796
12
来自主题: Military版 - “detoxify
I Gory Details I
Fact or Fiction: Can You Really Sweat Out Toxins?
There are plenty of good reasons to work up a sweat. Detoxifying your body
isn’t one of them.
Sweating is a bodily function that used to be taboo, with women in
particular being told they don’t sweat, they glow. But look at any fashion
magazine or beauty blog today, and you’ll find that sweat is in style. From
infrared saunas to hot yoga, towel-soaking activities are being touted not
only as relaxation tools, but also as ways t... 阅读全帖
q*d
发帖数: 22178
13
☆─────────────────────────────────────☆
swjtuer (swjtuer) 于 (Tue Mar 30 23:56:30 2010, 美东) 提到:
星期一
早餐 牛奶,煮鸡蛋,玉米馒头,榨菜
早点 芦柑
午餐 中大:绿豆饭,木须肉,海米冬瓜,棒骨菠菜汤
小婴:绿豆饭,三叶瓜炒肉,海米冬瓜,棒骨菠菜汤
午点 冰糖山楂水,蔬菜饼
晚餐 棒骨冬苋菜瘦肉粥,卤肉秋叶夹馍

星期二
早餐 牛奶,蒸鸡蛋,枣泥糕
早点 香蕉
午餐 中大:胡萝卜饭,芹菜炒牛肉,珊瑚豆腐,棒骨凤尾汤
小婴:胡萝卜饭,芹菜炒肉,珊瑚豆腐,棒骨凤尾汤
午点 果汁,卤猪肝
晚餐 豌豆肉末焖饭,番茄虾皮紫菜汤
星期三
早餐 南瓜粥,卤蛋,如意肉卷
早点 脐橙
午餐 中大:金银饭,咸烧白,海米儿菜,棒骨冬苋菜汤
小婴:金银饭,樱桃肉,海米儿菜,棒骨冬苋菜汤
午点 牛奶,蛋卷
晚餐 米饭,蒜苔炒肉,芙蓉蒸蛋,棒骨海带萝卜汤
星期四
早餐 牛奶,蒸鸡蛋,奶香馒头
早点 苹果
午餐 中大:南瓜饭,什锦鱼丸,韭菜炒豆干,番茄菌类鱼汤
... 阅读全帖
k****s
发帖数: 1209
14
来自主题: Biology版 - 蜕皮素
原文在
http://www.skizit.biz/2013/07/21/ecdysone-insect-hormone-an-ind
Ecdysone Insect Hormone Switches on Disease
21 Jul 2013 | ECDYSONE
MORGELLONS:
INSECT HORMONE ECDYSONE TRIGGERS GENETIC CHANGES
TO BUILD NEW HAIR, SKIN, NAILS and CAUSE DISEASES
SkizitGesture-2013
Morgellons is a military grade entomological terror weapon being used to
torture and kill innocent civilians. The medical community has not been
informed about this disease and its complexity keeps it from being properly
identified, ... 阅读全帖
D*****l
发帖数: 554
15
来自主题: MedicalCareer版 - 看EHEC疫情新闻复习FA/UW
肆虐欧美 全球恐慌 研究称恶菌与艾滋肠毒同源
中新网6月4日电 据香港《文汇报》4日报道,肆虐欧洲的肠出血性大肠杆菌(EHEC)疫情
持续蔓延,更有向全球扩散迹象。世界卫生组织(WHO)表示,美国与捷克也相继传出确
诊病例,现时疫情已蔓延至13个国家。中国深圳华大基因研究院和德国一家大学昨日宣
布,中德科学家联合对本次流行的病菌进行了全基因组测序,结果显示,该病菌与艾滋
病患者腹泻标本中的大肠杆菌同源性超过93%,兼具侵袭、产毒、抗药等多种“凶性”
,难以治疗,死亡率偏高。
深圳华大的初步分析结果显示,这次肆虐欧洲的血清型0104大肠杆菌,该病菌带有
新型特异基因,与2002年从中非共和国艾滋病患者腹泻标本中分离的肠聚集性大肠杆菌
55989菌株,同源性超过93%,同时它还通过基因水平转移,获得肠出血性大肠杆菌的毒
力基因和毒力相关质粒,这可能与该菌株强毒性和重症感染有关。
变种新基因 夺18人命
同日德国明斯特大学医学院卫生研究所表示,造成本次疫情的菌株是0104:H4大肠
杆菌的一个变种。然而世卫发言人表示,是次导致多人死亡的大肠杆菌,过往曾在人类
身上出现。
EHEC疫情蔓延,德... 阅读全帖
s********n
发帖数: 26222
16
方舟子在此文中说“虫子不吃的, 人能吃吗”是中国人的质疑, 而美国人是不会问这
样的问题的, 这显然是骗人的。见下文和其中引用的文献, 其中不少是美国人的科研

"Comments on the human health impact of Bacillus thuringiensis toxin gene
product in genetically modified crops"
EPA Review Docket Number OPP-00678B
Professor Joe Cummins
Professor Emeritus of Genetics
University of Western Ontario
I have studied the Environment Protection Agency (EPA) document "Bt Plant-
Pesticides Biopesticides Registration Action Document B. HUMAN HEALTH
ASSESSMENT" and comment in the following ... 阅读全帖
d********a
发帖数: 3698
17
http://www.ncbi.nlm.nih.gov/pubmed/21338670
我上面转的这个文章2011年5月发表于Reproductive Toxicology,
是第一篇关于杀虫剂改基因植物的毒性文章,发表1个多月就有3个引用。
引发了很多同行讨论,这个说明就是欧美专业人士也不是很清楚改基因食物的毒性。
Dear Friends and colleagues,
RE: Maternal and Fetal Exposure to Pesticides Associated with GM Foods
An article in press in Reproductive Toxicology is the first to highlight the
presence of pesticides associated with foods genetically engineered to
tolerate various herbicides and insecticides in pregnant and non-pregnant
women. The study i... 阅读全帖
p********3
发帖数: 5750
18
再让你长长见识:大家看和文献3-6相关的那句话,专门提出了中药的肾脏毒性问题,表明实际上的肾脏毒性比原先预期想象的还要普遍。
大家没有忘记在对Herb Medicine管制更严格的欧盟对中药 Ban了吧。 我上篇文献里面说了欧盟对Herb的管理对美国严格, 谈得比较细,有兴趣的可以仔细阅读。
Author
Marc E De Broe, MD, PhD Section Editor
Gary C Curhan, MD, ScD Deputy Editor
John P Forman, MD, MSc

Last literature review version 19.2: May 2011 | This topic last updated:
June 15, 2010
INTRODUCTION — In 1991, physicians in Belgium noted an increasing number of
women who presented with acute, often near end-stage renal disease
following expo... 阅读全帖
I******a
发帖数: 3812
19
都歇菜吧,你们见过常年吸大麻的人么? 俩眼儿发直急性超差,痴呆一样。米国那大
麻合法话是骗SB的。
THC Detox:
Tetrahydro cannabinol or THC is a known active toxin in marijuana. THC is a
neuro-toxin. Neuro- means ‘nerve’ and toxin means ‘poison’. THC can
damage the nerve cells of the body. THC can act like a virus by changing the
nerve and other cells it invades. This is called cell mutation. If this
wasn’t bad enough, THC detox is made difficult because cannabinols are fat
soluble and store in fat cells and other cells. The fat cells eventuall... 阅读全帖
I******a
发帖数: 3812
20
都歇菜吧,你们见过常年吸大麻的人么? 俩眼儿发直急性超差,痴呆一样。米国那大
麻合法话是骗SB的。
THC Detox:
Tetrahydro cannabinol or THC is a known active toxin in marijuana. THC is a
neuro-toxin. Neuro- means ‘nerve’ and toxin means ‘poison’. THC can
damage the nerve cells of the body. THC can act like a virus by changing the
nerve and other cells it invades. This is called cell mutation. If this
wasn’t bad enough, THC detox is made difficult because cannabinols are fat
soluble and store in fat cells and other cells. The fat cells eventuall... 阅读全帖
k*******2
发帖数: 1429
21
BT proteins are toxic to human cells
Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins
alone or with a glyphosate-based herbicide
Mesnage R., Clair E., Gress S., Then C., Székács A., Séralini G.-E
Article first published online: 15 FEB 2012, Journal of Applied Toxicology
DOI: 10.1002/jat.2712
ABSTRACT
The study of combined effects of pesticides represents a challenge for
toxicology. In the case of the new growing generation of genetically
modified (GM) plants with stacked t... 阅读全帖
t*****s
发帖数: 2933
22
PS 地区污染还是很严重的。
SEATTLE - On the eve of Halloween, a local environmental advocacy group
hopes to add a little fright to the night by releasing its list of scary
facts about pollution and the Puget Sound.
According to Environment Washington, the state's iconic waterway is haunted
by stormwater runoff and toxic dumping, and now is the time for federal
environmental leaders to step up and protect the Sound from unchecked
pollution.
Below is a condensed version of Environment Washington's list of Fri... 阅读全帖
U******u
发帖数: 5829
23
K, 机油事小,健康和命事大,转个才看来的吧----
CAR AIR-CONDITIONING - VERY IMPORTANT!

WHY? Car Air-conditioning - No wonder more folks are dying from cancer than
ever before. We wonder where this stuff comes from but here is an
example that explains a lot of the cancer causing incidents.

Many people are in their cars first thing in the morning and the last thing
at night, 7 days a week.
As I read this, it makes me feel guilty and ill.
Please pass this on to as many p... 阅读全帖
w******e
发帖数: 953
24
How safe does transgenic food need to be?
Laura DeFrancesco1
Journal name:
Nature Biotechnology
Volume:
31,
Pages:
794–802
Year published:
(2013)
DOI:
doi:10.1038/nbt.2686
Published online 10 September 2013 Corrected online 26 September 2013
Article tools
PDF
How safe does transgenic food need to be?
Download as PDF (812 KB) View interactive PDF in ReadCube
Citation
Reprints
Rights & permissions
Article metrics
Disputes over how to assess a foodstuff's safety continue to play into
public fears a... 阅读全帖
H********g
发帖数: 43926
25
来自主题: Joke版 - 眼镜蛇毒液对血液的影响
It may sound scary, but snake venom can be very useful to humans. In a study
published last year in the Journal Of Biological Chemistry researchers
noted important medical uses of the sinister stuff.
"Snake venom contains a vast number of toxins that target proteins in
platelets," Yonchol Shin, an associate professor at Kogakuin University who
specializes in snake toxins told ScienceDaily. "Some of those toxins prevent
platelets from clotting, which can lead to profuse bleeding in snake bite
vic... 阅读全帖
B*****n
发帖数: 5
26
来自主题: Biology版 - About GM crops
Anyone has inside information on this issue ?
http://www.gmwatch.org/component/content/article/11573-gm-indus
In the US, under the Federal Food, Drug and Cosmetic Act of 1938, the FDA is
responsible for ensuring that food is safe to eat, although by statute, it
regulates only food additives. By that definition, most crops are exempt
from FDA approval, although companies tasked with ensuring their products
are safe often voluntarily submit a considerable amount of information.
Certain types of co... 阅读全帖
b******n
发帖数: 80
27
楼上的,我 查过了HPV-18是病毒。
我做了一个toxin,之前他是没有毒性的,然后我想注射到组织内,想用cancer特有的
蛋白的antibody连上,然后利用在局部区间高溶度,是的toxin进入细胞内,也就是穿
刺,最后将保护toxin的外壳去掉,利用toxin的来杀死cancer cell.所以我的问题是:
什么的蛋白是特有的biomarker for hela cell or MCF some other cancer cell?
w*********s
发帖数: 2136
28
【 以下文字转载自 Complain 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Complain
标 题: 投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大
发信站: BBS 未名空间站 (Tue Mar 22 18:47:29 2011, 美东)
事关每个人身心健康。你们凭什么封禁医药界的负面消息和非主流消息?
发信人: whiteclouds (/ 参考消息 /), 信区: Parenting
标 题: CDC to Study Vaccines and Autism
发信站: BBS 未名空间站 (Tue Mar 22 18:44:33 2011, 美东)
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism ... 阅读全帖
w*l
发帖数: 2550
29
http://somloquesembrem.files.wordpress.com/2010/07/arisleblanc2
该文检测两种除草剂(GLYP和GLUF)及其代谢物,以及一种CryAb1 Bt毒蛋白在母体及胎
儿血液的含量。
结果:
GLYP及其代谢物:未检测到。
GLUF未检测到。其代谢物3-MPPA普遍存在 (On the other hand,3-MPPA(the
metabolite of GLUF)was detected in 100% of maternal and umbilical cord blood
samples,and in 67% of the nonpregnant women’s blood samples),含量较高 (
8-417 ng/mL)。
GLUF对人的正常发育有不利影响 (Garciaetal. [37] investigated the potential
teratogenic effects of GLUF in humans found and increased risk of congenital
malforma... 阅读全帖
f********1
发帖数: 698
30
结合一下最近版上的中餐西餐之争,真搞笑啊 果然是互相鄙视啊~~倒也扯平了
http://www.chicagotribune.com/news/local/ct-met-carp-microtoxin
Biologist Jon Amberg has spent the last two years obsessed with fish guts,
laboring over a singular challenge: Develop a poison pill that will kill
Asian carp and leave other fish unscathed.
Voracious and freakishly resilient, the fish has left a trail of destruction
on its decades-long migration up the Mississippi River and into Illinois,
seemingly undeterred by the ordinary ammo of invasive spe... 阅读全帖
l*h
发帖数: 4124
31
中国留美学生代购蓖麻毒素被判十六年
一名曾在美国纽约大学就读的中国男子因在网上代购剧毒的蓖麻毒素,结果找的卖家是
联邦调查局(FBI)卧底探员,8日被曼哈顿一家联邦法院判处16年监禁。
被告名为乐成(音译),现年22岁,曾在纽约大学就读物理学专业,不久离校,在独自
租住的曼哈顿一处公寓内做起了网络代购生意。
检察官说,2014年12月,在一家名为“进化”的网络黑市网站上,向网名为“黑暗马尔
特”的商贩打听购买蓖麻毒素事宜,称自己有不少二手买家。
“黑暗马尔特”实际上是当时在调查黑市不法行为的联邦调查局卧底。
法庭文件显示,乐成在同“黑暗马尔特”聊天时写道,“如果你能把(蓖麻毒素)做成
简易药片,肯定会大卖。”他还在发给对方的信息中说,把蓖麻毒素药片混入普通维生
素药瓶,目标对象每天吃一片,“迟早会因摄入的剧毒药片而死掉”。
蓖麻毒素是一种致命剧毒物,而且没有解药。美国媒体先前报道,“基地”组织曾计划
用蓖麻毒素、氰化物等致命毒剂对美国发动恐怖袭击。
乐成在聊天记录中还写道,“毕竟我们卖的东西是用来杀人,风险越小,越有效,也就
越好。”
联邦调查局探员把假的蓖麻毒素邮寄给乐成。提货时,乐... 阅读全帖
f***y
发帖数: 4447
32
https://tech.sina.com.cn/d/f/2018-09-07/doc-ihitesuz6317283.shtml
今日,顶尖学术期刊《科学》杂志在其官网上在线发表了最新一批论文。其中,我们很
高兴地看到一篇来自颜宁课题组的研究。值得一提的是,这是在过去的这个暑假里,颜
宁课题组发表的第三篇《科学》长文(Research Article)。在今天的这篇文章里,我
们也将为各位读者介绍和回顾这些进展。
图片来源:普林斯顿大学
9月6日在线发表:Structure of the human voltage-gated sodium channel Nav1
.4 in complex with β1
9月6日,颜宁课题组的这项最新论文正式在线发表,这是关于电压门控钠离子通道
(Nav)的研究。尽管Nav可能对许多人类疾病有着潜在影响,但几十年来的大量探索,
依旧没有解析出任何来自人类的Nav通道结构,这也在很大程度上影响了我们对其作用
机理的理解,限制了相应的新疗法开发。
人类Nav1.4-β1复合体的结构(图片来源:《科学》)
在这项研究里,研究人员们使用冷冻电镜技术,报... 阅读全帖
m**p
发帖数: 7
33
https://www.nytimes.com/2019/08/05/health/germs-fort-detrick-biohazard.html
Deadly Germ Research Is Shut Down at Army Lab Over Safety Concerns
Problems with disposal of dangerous materials led the government to suspend
research at the military’s leading biodefense center.
By Denise Grady
Aug. 5, 2019
Safety concerns at a prominent military germ lab have led the government to
shut down research involving dangerous microbes like the Ebola virus.
“Research is currently on hold,” the United States A... 阅读全帖
m**p
发帖数: 7
34
https://www.nytimes.com/2019/08/05/health/germs-fort-detrick-biohazard.html
Deadly Germ Research Is Shut Down at Army Lab Over Safety Concerns
Problems with disposal of dangerous materials led the government to suspend
research at the military’s leading biodefense center.
By Denise Grady
Aug. 5, 2019
Safety concerns at a prominent military germ lab have led the government to
shut down research involving dangerous microbes like the Ebola virus.
“Research is currently on hold,” the United States A... 阅读全帖
m**p
发帖数: 7
35
https://www.nytimes.com/2019/08/05/health/germs-fort-detrick-biohazard.html
Deadly Germ Research Is Shut Down at Army Lab Over Safety Concerns
Problems with disposal of dangerous materials led the government to suspend
research at the military’s leading biodefense center.
By Denise Grady
Aug. 5, 2019
Safety concerns at a prominent military germ lab have led the government to
shut down research involving dangerous microbes like the Ebola virus.
“Research is currently on hold,” the United States A... 阅读全帖
w*********s
发帖数: 2136
36
来自主题: WorldNews版 - CDC to Study Vaccines and Autism (转载)
【 以下文字转载自 Parenting 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Parenting
标 题: CDC to Study Vaccines and Autism
发信站: BBS 未名空间站 (Tue Mar 22 18:44:33 2011, 美东)
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism as a
possible clinical outcome of immunization, as part of its newly adopted 5-
year research agenda for vaccine safety, the agency said on its website.
The CDC wi... 阅读全帖
w*********s
发帖数: 2136
37
【 以下文字转载自 Complain 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Complain
标 题: 投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大
发信站: BBS 未名空间站 (Tue Mar 22 18:47:29 2011, 美东)
投诉人: Whiteclouds
投诉对象:我爱宝宝版主mitbbx及版副catdoudou
投诉标题:投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大家长
投诉目标:罢免
投诉理由:
1. 事关每个人身心健康。你们凭什么封禁医药界的负面消息和非主流消息?
2. 关于疫苗利弊的讨论早已进入主流媒体了。你凭什么不让大家看到?
3. 药品(包括疫苗)近年屡有recall. 你凭什么禁止有关信息来误导家里有小宝宝的父母去盲目迷信药品质量?
4. 美加庸医遍地都是,医疗事故屡见不鲜。你凭什么制造版面气氛让家长对处方和诊断不过脑子的去盲信?
5. 凡事要听多方面意见,有点科学精神,你们动辄删贴封人缺乏领导版面的基本素质
6. 为人父母要首先自己要学会尊重不同意见,... 阅读全帖
w*********s
发帖数: 2136
38
【 以下文字转载自 Complain 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Complain
标 题: 投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大
发信站: BBS 未名空间站 (Tue Mar 22 18:47:29 2011, 美东)
投诉人: Whiteclouds
投诉对象:我爱宝宝版主mitbbx及版副catdoudou
投诉标题:投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大家长
投诉目标:罢免
投诉理由:
1. 事关每个人身心健康。你们凭什么封禁医药界的负面消息和非主流消息?
2. 关于疫苗利弊的讨论早已进入主流媒体了。你凭什么不让大家看到?
3. 药品(包括疫苗)近年屡有recall. 你凭什么禁止有关信息来误导家里有小宝宝的父母去盲目迷信药品质量?
4. 美加庸医遍地都是,医疗事故屡见不鲜。你凭什么制造版面气氛让家长对处方和诊断不过脑子的去盲信?
5. 凡事要听多方面意见,有点科学精神,你们动辄删贴封人缺乏领导版面的基本素质
6. 为人父母要首先自己要学会尊重不同意见,... 阅读全帖
p**********g
发帖数: 9558
39
来自主题: Living版 - 是不是laminate算了。
半斤八两,真这么算,恐怕都有问题
Most new flooring contains carcinogens, environmental toxins, particularly
formaldehyde. Levels of these chemicals are particularly high in carpet, but
can also have dangerous levels in laminate, vinyl and hardwood as well.
These toxins can cause a number of problems from asthma to cancer. New or
old, your flooring can still be an issue. Older carpet is the keeper of all,
especially dust mites, pesticides and other toxins brought in from shoes
can be left to linger on carpet for... 阅读全帖
w*********s
发帖数: 2136
40
来自主题: Medicine版 - CDC to Study Vaccines and Autism (转载)
【 以下文字转载自 Parenting 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Parenting
标 题: CDC to Study Vaccines and Autism
发信站: BBS 未名空间站 (Tue Mar 22 18:44:33 2011, 美东)
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism as a
possible clinical outcome of immunization, as part of its newly adopted 5-
year research agenda for vaccine safety, the agency said on its website.
The CDC wi... 阅读全帖
w*********s
发帖数: 2136
41
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism as a
possible clinical outcome of immunization, as part of its newly adopted 5-
year research agenda for vaccine safety, the agency said on its website.
The CDC will also study mitochondrial dysfunction and the potential risk for
post-vaccine "neurological deterioration," and convene an expert panel on
the feasibili... 阅读全帖
w*********s
发帖数: 2136
42
来自主题: Parenting版 - CDC to Study Vaccines and Autism
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism as a
possible clinical outcome of immunization, as part of its newly adopted 5-
year research agenda for vaccine safety, the agency said on its website.
The CDC will also study mitochondrial dysfunction and the potential risk for
post-vaccine "neurological deterioration," and convene an expert panel on
the feasibili... 阅读全帖
m****r
发帖数: 6639
43
the random people just pick the cans out of the trash, i don't see how that
spreads toxins.
but that is besides the point, right? if you own the toxin, then it is your
responsibility it doesn't get spread. and leaving it at a public place is
not how it should be done safely. they should make sure the toxins are not
accessible by anyone.

.
ensure".
is
c******e
发帖数: 545
44
it takes much longer time for some species of clam (including butter clam)
to purge the PSP toxin. PSP toxin is produced by some species of algae.
Clams consume the algae and the PSP toxin get accumulated in their body.
http://www.doh.wa.gov/CommunityandEnvironment/Shellfish/Biotoxi
P****D
发帖数: 11146
45
http://www.sciencemag.org/content/336/6086/1248.full
Published Online June 6 2012
Science 8 June 2012:
Vol. 336 no. 6086 pp. 1248-1250
DOI: 10.1126/science.336.6086.1248
News
News
My Microbiome and Me
Mara Hvistendahl
Zhao Liping combines traditional Chinese medicine and studies of gut
microbes to understand and fight obesity.
Introduction
Perspectives
ScienceIs It Time for a Metagenomic Basis of Therapeutics?
ScienceHonor Thy Gut Symbionts Redux
Science Translational Med... 阅读全帖
j****y
发帖数: 1714
46
来自主题: loseweight版 - 如何从barcode里解读GMO食物
I am not so sure GMO is harmless.
see http://articles.mercola.com/sites/articles/archive/2013/10/13/cummins-gmo-labeling.aspx
Why GE Cotton Is a Major Health Hazard
About 20 percent of genetically engineered (GE) crops are used in processed
food. The remaining 80 percent of GE crops go into (non-organic) animal feed
, cotton, biofuels, cosmetics, and nutritional supplements. This is one of
the reasons why I recommend eating organically-raised, grass-fed or pastured
meats only and shopping for ce... 阅读全帖
B********e
发帖数: 19317
47
【 以下文字转载自 WaterWorld 讨论区 】
发信人: ruomu (ruomu), 信区: WaterWorld
标 题: 一个学长天天玩dota 结果GRE接近满分 让你见识下。。。
发信站: BBS 未名空间站 (Fri Apr 1 10:58:57 2011, 美东)
总的来说,DoTA是一个文化包容性很强的游戏,而且DOTA中文版翻译的还是非常非常好
的~~~
(既然这么多人看。。lz顺征人交流魔兽对战,是1v1对战喔)
后文会出现的一些常用缩写:
War3:warcraft 3 魔兽争霸3
RA:red alert 红色警戒系列
SC: star craft 星际争霸
CoD:call of duty 使命召唤
还有一些游戏的名称在文中会有注释。
好了,正文:
关于Dota和一些游戏中的GRE词汇
A字头
Abaddon :DOTA中地狱领主的名字。本意为地狱,恶魔。是圣经里的亚玻伦 (地狱的
使者)。
abomination:war3中的憎恶。abominate痛恨,憎恶。
aegis:immortal aeg... 阅读全帖
B********s
发帖数: 1617
48
来自主题: PhotoGear版 - 波多黎各的行程和照片若干
我靠,千万不要误导,那个水还是不要喝的好。
https://microbewiki.kenyon.edu/images/0/0c/Saxitoxin.jpg
Pyrodinium bahamense, along with many other dinoflagellates, are known for
secreting toxins that cause Paralytic Shellfish Poisoning (PSP). The group
of toxins that are released by Pyrodinium bahamense are known as saxitoxins.
While not particularly dangerous out in the open ocean, the toxin is
sequestered in molluscian shellfish and is dangerous to mollusk consumers.
PSP has a 15% mortality rate in the human populati... 阅读全帖
w*********s
发帖数: 2136
49
【 以下文字转载自 Complain 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Complain
标 题: 投诉我爱宝宝版主mitbbx及版副catdoudou大搞新闻网禁误导广大
发信站: BBS 未名空间站 (Tue Mar 22 18:47:29 2011, 美东)
事关每个人身心健康。你们凭什么封禁医药界的负面消息和非主流消息?
发信人: whiteclouds (/ 参考消息 /), 信区: Parenting
标 题: CDC to Study Vaccines and Autism
发信站: BBS 未名空间站 (Tue Mar 22 18:44:33 2011, 美东)
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism ... 阅读全帖
w*********s
发帖数: 2136
50
来自主题: WaterWorld版 - CDC to Study Vaccines and Autism (转载)
【 以下文字转载自 Parenting 讨论区 】
发信人: whiteclouds (/ 参考消息 /), 信区: Parenting
标 题: CDC to Study Vaccines and Autism
发信站: BBS 未名空间站 (Tue Mar 22 18:44:33 2011, 美东)
CDC to Study Vaccines and Autism
HuffingtonPost.com
David Kirby
Author/Journalist
Posted: March 18, 2011 05:46 PM
The Centers for Disease Control and Prevention wants to study autism as a
possible clinical outcome of immunization, as part of its newly adopted 5-
year research agenda for vaccine safety, the agency said on its website.
The CDC wi... 阅读全帖
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